7V94
Cryo-EM structure of the Cas12c2-sgRNA-target DNA ternary complex
Summary for 7V94
Entry DOI | 10.2210/pdb7v94/pdb |
EMDB information | 31807 31808 |
Descriptor | Cas12c2, sgRNA, target DNA (target strand), ... (4 entities in total) |
Functional Keywords | cas12c, c2c3, sgrna, target dna, crispr, rna binding protein-rna-dna complex, rna binding protein/rna/dna |
Biological source | uncultured archaeon More |
Total number of polymer chains | 4 |
Total formula weight | 194795.44 |
Authors | Kurihara, N.,Hirano, H.,Tomita, A.,Kobayashi, K.,Kusakizako, T.,Nishizawa, T.,Yamashita, K.,Nishimasu, H.,Nureki, O. (deposition date: 2021-08-24, release date: 2022-04-13, Last modification date: 2024-06-12) |
Primary citation | Kurihara, N.,Nakagawa, R.,Hirano, H.,Okazaki, S.,Tomita, A.,Kobayashi, K.,Kusakizako, T.,Nishizawa, T.,Yamashita, K.,Scott, D.A.,Nishimasu, H.,Nureki, O. Structure of the type V-C CRISPR-Cas effector enzyme. Mol.Cell, 82:1865-1877.e4, 2022 Cited by PubMed: 35366394DOI: 10.1016/j.molcel.2022.03.006 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.7 Å) |
Structure validation
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