7V94

Cryo-EM structure of the Cas12c2-sgRNA-target DNA ternary complex

Summary for 7V94

Entry DOI	10.2210/pdb7v94/pdb
EMDB information	31807 31808
Descriptor	Cas12c2, sgRNA, target DNA (target strand), ... (4 entities in total)
Functional Keywords	cas12c, c2c3, sgrna, target dna, crispr, rna binding protein-rna-dna complex, rna binding protein/rna/dna
Biological source	uncultured archaeon More
Total number of polymer chains	4
Total formula weight	194795.44
Authors	Kurihara, N.,Hirano, H.,Tomita, A.,Kobayashi, K.,Kusakizako, T.,Nishizawa, T.,Yamashita, K.,Nishimasu, H.,Nureki, O. (deposition date: 2021-08-24, release date: 2022-04-13, Last modification date: 2022-06-01)
Primary citation	Kurihara, N.,Nakagawa, R.,Hirano, H.,Okazaki, S.,Tomita, A.,Kobayashi, K.,Kusakizako, T.,Nishizawa, T.,Yamashita, K.,Scott, D.A.,Nishimasu, H.,Nureki, O. Structure of the type V-C CRISPR-Cas effector enzyme. Mol.Cell, 82:1865-1877.e4, 2022 Cited by PubMed: 35366394 DOI: 10.1016/j.molcel.2022.03.006 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.6 Å)

Structure validation