1M8P
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1D6J
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1I2D
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2QVW
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4W5T
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5JS1
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![BU of 5js1 by Molmil](/molmil-images/mine/5js1) | Human Argonaute2 Bound to an siRNA | 分子名称: | MAGNESIUM ION, PHENOL, Protein argonaute-2, ... | 著者 | Schirle, N.T, MacRae, I.J. | 登録日 | 2016-05-07 | 公開日 | 2016-07-20 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.499 Å) | 主引用文献 | Structural Analysis of Human Argonaute-2 Bound to a Modified siRNA Guide. J.Am.Chem.Soc., 138, 2016
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5WEA
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![BU of 5wea by Molmil](/molmil-images/mine/5wea) | Human Argonaute2 Helix-7 Mutant | 分子名称: | PHENOL, Protein argonaute-2, RNA (5'-R(P*AP*AP*AP*AP*AP*AP*AP*U)-3') | 著者 | Schirle, N.T, Klum, S.M, MacRae, I.J. | 登録日 | 2017-07-08 | 公開日 | 2017-11-22 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.12 Å) | 主引用文献 | Helix-7 in Argonaute2 shapes the microRNA seed region for rapid target recognition. EMBO J., 37, 2018
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7SWF
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7SWQ
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7SVA
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4OLB
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4OLA
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4W5R
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4W5Q
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4GH9
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![BU of 4gh9 by Molmil](/molmil-images/mine/4gh9) | Crystal structure of Marburg virus VP35 RNA binding domain | 分子名称: | ACETATE ION, Polymerase cofactor VP35 | 著者 | Bale, S, Jean-Philippe, J, Bornholdt, Z.A, Kimberlin, C.K, Halfmann, P, Zandonatti, M.A, Kunert, J, Kroon, G.J.A, Kawaoka, Y, MacRae, I.J, Wilson, I.A, Saphire, E.O. | 登録日 | 2012-08-07 | 公開日 | 2012-08-15 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Marburg Virus VP35 Can Both Fully Coat the Backbone and Cap the Ends of dsRNA for Interferon Antagonism. Plos Pathog., 8, 2012
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4GHA
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![BU of 4gha by Molmil](/molmil-images/mine/4gha) | Crystal structure of Marburg virus VP35 RNA binding domain bound to 12-bp dsRNA | 分子名称: | Polymerase cofactor VP35, RNA (5'-R(*CP*UP*AP*GP*AP*CP*GP*UP*CP*UP*AP*G)-3') | 著者 | Bale, S, Jean-Philippe, J, Bornholdt, Z.A, Kimberlin, C.K, Halfmann, P, Zandonatti, M.A, Kunert, J, Kroon, G.J.A, Kawaoka, Y, MacRae, I.J, Wilson, I.A, Saphire, E.O. | 登録日 | 2012-08-07 | 公開日 | 2012-08-22 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Marburg Virus VP35 Can Both Fully Coat the Backbone and Cap the Ends of dsRNA for Interferon Antagonism. Plos Pathog., 8, 2012
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3KS4
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![BU of 3ks4 by Molmil](/molmil-images/mine/3ks4) | Crystal structure of Reston ebolavirus VP35 RNA binding domain | 分子名称: | Polymerase cofactor VP35 | 著者 | Kimberlin, C.R, Bornholdt, Z.A, Li, S, Woods, V.L, Macrae, I.J, Saphire, E.O. | 登録日 | 2009-11-20 | 公開日 | 2010-01-12 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Ebolavirus VP35 uses a bimodal strategy to bind dsRNA for innate immune suppression. Proc.Natl.Acad.Sci.USA, 107, 2009
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3KS8
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![BU of 3ks8 by Molmil](/molmil-images/mine/3ks8) | Crystal structure of Reston ebolavirus VP35 RNA binding domain in complex with 18bp dsRNA | 分子名称: | 5'-R(*AP*GP*AP*AP*GP*GP*AP*GP*GP*GP*AP*GP*GP*GP*AP*GP*GP*A)-3', 5'-R(*UP*CP*CP*UP*CP*CP*CP*UP*CP*CP*CP*UP*CP*CP*UP*UP*CP*U)-3', Polymerase cofactor VP35 | 著者 | Kimberlin, C.R, Bornholdt, Z.A, Li, S, Woods, V.L, Macrae, I.J, Saphire, E.O. | 登録日 | 2009-11-20 | 公開日 | 2010-01-12 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.401 Å) | 主引用文献 | Ebolavirus VP35 uses a bimodal strategy to bind dsRNA for innate immune suppression. Proc.Natl.Acad.Sci.USA, 107, 2009
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3Q7C
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![BU of 3q7c by Molmil](/molmil-images/mine/3q7c) | Exonuclease domain of Lassa virus nucleoprotein bound to manganese | 分子名称: | MANGANESE (II) ION, Nucleoprotein, PHOSPHATE ION, ... | 著者 | Hastie, K.M, Kimberlin, C.R, Zandonatti, M.A, MacRae, I.J, Saphire, E.O. | 登録日 | 2011-01-04 | 公開日 | 2011-02-09 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structure of the Lassa virus nucleoprotein reveals a dsRNA-specific 3' to 5' exonuclease activity essential for immune suppression. Proc.Natl.Acad.Sci.USA, 108, 2011
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3Q7B
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![BU of 3q7b by Molmil](/molmil-images/mine/3q7b) | Exonuclease domain of Lassa virus nucleoprotein | 分子名称: | Nucleoprotein, PHOSPHATE ION, ZINC ION | 著者 | Hastie, K.M, Kimberlin, C.R, Zandonatti, M.A, MacRae, I.J, Saphire, E.O. | 登録日 | 2011-01-04 | 公開日 | 2011-02-09 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of the Lassa virus nucleoprotein reveals a dsRNA-specific 3' to 5' exonuclease activity essential for immune suppression. Proc.Natl.Acad.Sci.USA, 108, 2011
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5JS2
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5KI6
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4W5N
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![BU of 4w5n by Molmil](/molmil-images/mine/4w5n) | The Crystal Structure of Human Argonaute2 Bound to a Defined Guide RNA | 分子名称: | MAGNESIUM ION, PHENOL, Protein argonaute-2, ... | 著者 | Schirle, N.T, Sheu-Gruttadauria, J, MacRae, I.J. | 登録日 | 2014-08-18 | 公開日 | 2014-11-12 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Gene regulation. Structural basis for microRNA targeting. Science, 346, 2014
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4W5O
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1JHD
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![BU of 1jhd by Molmil](/molmil-images/mine/1jhd) | Crystal Structure of Bacterial ATP Sulfurylase from the Riftia pachyptila Symbiont | 分子名称: | BROMIDE ION, SULFATE ADENYLYLTRANSFERASE, SULFATE ION | 著者 | Beynon, J.D, MacRae, I.J, Huston, S.L, Nelson, D.C, Segel, I.H, Fisher, A.J. | 登録日 | 2001-06-27 | 公開日 | 2001-12-07 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structure of ATP sulfurylase from the bacterial symbiont of the hydrothermal vent tubeworm Riftia pachyptila. Biochemistry, 40, 2001
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