3KS4
Crystal structure of Reston ebolavirus VP35 RNA binding domain
Summary for 3KS4
| Entry DOI | 10.2210/pdb3ks4/pdb |
| Related | 3FKE 3KS8 |
| Descriptor | Polymerase cofactor VP35 (2 entities in total) |
| Functional Keywords | ebolavirus, rna-binding protein, protein-rna complex, interferon, reston, host cytoplasm, interferon antiviral system evasion, rna replication, rna-binding, transcription, virion, viral protein, rna binding protein |
| Biological source | Reston ebolavirus (REBOV) |
| Cellular location | Virion: Q8JPY0 |
| Total number of polymer chains | 2 |
| Total formula weight | 41138.85 |
| Authors | Kimberlin, C.R.,Bornholdt, Z.A.,Li, S.,Woods, V.L.,Macrae, I.J.,Saphire, E.O. (deposition date: 2009-11-20, release date: 2010-01-12, Last modification date: 2024-02-21) |
| Primary citation | Kimberlin, C.R.,Bornholdt, Z.A.,Li, S.,Woods, V.L.,Macrae, I.J.,Saphire, E.O. Ebolavirus VP35 uses a bimodal strategy to bind dsRNA for innate immune suppression. Proc.Natl.Acad.Sci.USA, 107:314-319, 2009 Cited by PubMed: 20018665DOI: 10.1073/pnas.0910547107 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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