7SWF

Cryo-EM structure of Arabidopsis Ago10-guide-target RNA complex in a central duplex conformation

Summary for 7SWF

• Entry DOI: 10.2210/pdb7swf/pdb
• EMDB information: 25446 25472
• Descriptor: Protein argonaute 10, RNA (5'-R(P*UP*GP*GP*AP*GP*UP*GP*UP*GP*AP*CP*AP*AP*UP*GP*GP*U)-3'), RNA (5'-R(P*CP*CP*AP*UP*UP*GP*UP*CP*AP*CP*AP*CP*UP*CP*CP*AP*A)-3'), ... (4 entities in total)
• Functional Keywords: mirna, sirna, rna silencing, argonaute, plant, gene regulation
• Biological source: Arabidopsis thaliana (thale cress); More
• Total number of polymer chains: 3
• Total formula weight: 123430.38

Authors

Xiao, Y.,MacRae, I.J. (deposition date: 2021-11-19, release date: 2022-08-03, Last modification date: 2022-10-05)

• Primary citation: Xiao, Y.,MacRae, I.J.; The molecular mechanism of microRNA duplex selectivity of Arabidopsis ARGONAUTE10.; Nucleic Acids Res., 50:10041-10052, 2022; PubMed: 35801914; DOI: 10.1093/nar/gkac571

Experimental method

ELECTRON MICROSCOPY (3.79 Å)