6G9A
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5FOV
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![BU of 5fov by Molmil](/molmil-images/mine/5fov) | HUMANISED MONOMERIC RADA IN COMPLEX WITH FHTG TETRAPEPTIDE | 分子名称: | DNA repair and recombination protein RadA, FHTG PEPTIDE, GLYCEROL, ... | 著者 | Scott, D.E, Marsh, M, Blundell, T.L, Abell, C, Hyvonen, M. | 登録日 | 2015-11-26 | 公開日 | 2016-03-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.739 Å) | 主引用文献 | Structure Activity Relationship of the Peptide Binding Motif Mediating the Rad51:Brca2 Protein-Protein Interaction. FEBS Lett., 590, 2016
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5JXC
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![BU of 5jxc by Molmil](/molmil-images/mine/5jxc) | SynGAP Coiled-coil trimer | 分子名称: | Ras/Rap GTPase-activating protein SynGAP | 著者 | Shang, Y, Zhang, M. | 登録日 | 2016-05-13 | 公開日 | 2016-09-28 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Phase Transition in Postsynaptic Densities Underlies Formation of Synaptic Complexes and Synaptic Plasticity. Cell, 166, 2016
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6G52
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![BU of 6g52 by Molmil](/molmil-images/mine/6g52) | CRYSTAL STRUCTURE OF THE CNMP BINDING DOMAIN OF THE MAGNESIUM TRANSPORTER CNNM4 | 分子名称: | Metal transporter CNNM4 | 著者 | Gimenez, P, Oyenarte, I, Hardy, S, Zubillaga, M, Merino, N, Blanco, F.J, Siliqi, D, Tremblay, M, Muller, D, Martinez-Cruz, L.A. | 登録日 | 2018-03-28 | 公開日 | 2019-04-10 | 最終更新日 | 2019-12-25 | 実験手法 | X-RAY DIFFRACTION (3.691 Å) | 主引用文献 | Structural Insights into the Intracellular Region of the Human Magnesium Transport Mediator CNNM4. Int J Mol Sci, 20, 2019
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6CCQ
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5F8T
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![BU of 5f8t by Molmil](/molmil-images/mine/5f8t) | The crystal structure of human Plasma Kallikrein in complex with its peptide inhibitor pkalin-2 | 分子名称: | CYS-PRO-LYS-ARG-PHE-M70-ALA-LEU-PHE-CYS, Plasma kallikrein light chain, SULFATE ION, ... | 著者 | Xu, M, Jiang, L, Xu, P, Luo, Z, Andreasen, P, Huang, M. | 登録日 | 2015-12-09 | 公開日 | 2016-12-14 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | The crystal structure of human Plasma Kallikrein in complex with its peptide inhibitor pkalin-2 To Be Published
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5F92
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![BU of 5f92 by Molmil](/molmil-images/mine/5f92) | Fumarate hydratase of Mycobacterium tuberculosis in complex with formate | 分子名称: | CHLORIDE ION, FORMIC ACID, Fumarate hydratase class II, ... | 著者 | Kasbekar, M, Fischer, G, Mott, B.T, Yasgar, A, Hyvonen, M, Boshoff, H.I, Abell, C, Barry, C.E, Thomas, C.J. | 登録日 | 2015-12-09 | 公開日 | 2016-06-22 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.859 Å) | 主引用文献 | Selective small molecule inhibitor of the Mycobacterium tuberculosis fumarate hydratase reveals an allosteric regulatory site. Proc.Natl.Acad.Sci.USA, 113, 2016
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5FUG
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![BU of 5fug by Molmil](/molmil-images/mine/5fug) | Crystal structure of a human YL1-H2A.Z-H2B complex | 分子名称: | HISTONE H2A.Z, HISTONE H2B TYPE 1-J, VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 72 HOMOLOG | 著者 | Latrick, C.M, Marek, M, Ouararhni, K, Papin, C, Stoll, I, Ignatyeva, M, Obri, A, Ennifar, E, Dimitrov, S, Romier, C, Hamiche, A. | 登録日 | 2016-01-27 | 公開日 | 2016-03-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Molecular Basis and Specificity of H2A.Z-H2B Recognition and Deposition by the Histone Chaperone Yl1 Nat.Struct.Mol.Biol., 23, 2016
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6G32
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![BU of 6g32 by Molmil](/molmil-images/mine/6g32) | Crystal structure of human geranylgeranyl diphosphate synthase mutant D188Y | 分子名称: | GLYCEROL, Geranylgeranyl pyrophosphate synthase | 著者 | Lisnyansky, M, Kapelushnik, N, Ben-Bassat, A, Marom, M, Loewenstein, A, Khananshvili, D, Giladi, M, Haitin, Y. | 登録日 | 2018-03-24 | 公開日 | 2018-10-17 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.281 Å) | 主引用文献 | Reduced Activity of Geranylgeranyl Diphosphate Synthase Mutant Is Involved in Bisphosphonate-Induced Atypical Fractures. Mol. Pharmacol., 94, 2018
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6TA5
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![BU of 6ta5 by Molmil](/molmil-images/mine/6ta5) | OprM-MexA complex from the MexAB-OprM Pseudomonas aeruginosa whole assembly reconstituted in nanodiscs | 分子名称: | Efflux pump membrane transporter, MexA family multidrug efflux RND transporter periplasmic adaptor subunit, Outer membrane protein OprM | 著者 | Glavier, M, Schoehn, G, Taveau, J.C, Phan, G, Daury, L, Lambert, O, Broutin, I. | 登録日 | 2019-10-29 | 公開日 | 2020-09-16 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Antibiotic export by MexB multidrug efflux transporter is allosterically controlled by a MexA-OprM chaperone-like complex. Nat Commun, 11, 2020
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5FLX
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![BU of 5flx by Molmil](/molmil-images/mine/5flx) | Mammalian 40S HCV-IRES complex | 分子名称: | 18S RRNA, 40S RIBOSOMAL PROTEIN S10, 40S RIBOSOMAL PROTEIN S11, ... | 著者 | Yamamoto, H, Collier, M, Loerke, J, Ismer, J, Schmidt, A, Hilal, T, Sprink, T, Yamamoto, K, Mielke, T, Burger, J, Shaikh, T.R, Dabrowski, M, Hildebrand, P.W, Scheerer, P, Spahn, C.M.T. | 登録日 | 2015-10-28 | 公開日 | 2015-12-23 | 最終更新日 | 2017-08-30 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Molecular Architecture of the Ribosome-Bound Hepatitis C Virus Internal Ribosomal Entry Site RNA. Embo J., 34, 2015
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5TZS
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![BU of 5tzs by Molmil](/molmil-images/mine/5tzs) | Architecture of the yeast small subunit processome | 分子名称: | 13 kDa ribonucleoprotein-associated protein, 18S ribosomal RNA, 3' domain-associated, ... | 著者 | Chaker-Margot, M, Barandun, J, Hunziker, M, Klinge, S. | 登録日 | 2016-11-22 | 公開日 | 2016-12-21 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (5.1 Å) | 主引用文献 | Architecture of the yeast small subunit processome. Science, 355, 2017
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6IVX
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![BU of 6ivx by Molmil](/molmil-images/mine/6ivx) | Discovery of the Second Generation ROR gamma Inhibitors Composed of an Azole Scaffold. | 分子名称: | (4S)-4-[4'-cyclopropyl-5-(2,2-dimethylpropyl)[3,5'-bi-1,2-oxazol]-3'-yl]-6-[(2,4-dichlorophenyl)amino]-6-oxohexanoic acid, Nuclear receptor ROR-gamma, Nuclear receptor corepressor 2 | 著者 | Noguchi, M, Nomura, A, Doi, S, Adachi, T. | 登録日 | 2018-12-04 | 公開日 | 2019-03-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Discovery of Second Generation ROR gamma Inhibitors Composed of an Azole Scaffold. J. Med. Chem., 62, 2019
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7RL1
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![BU of 7rl1 by Molmil](/molmil-images/mine/7rl1) | AAVrh.10-7x capsid | 分子名称: | Capsid protein VP1, DNA (5'-D(*CP*A)-3') | 著者 | Mietzsch, M, McKenna, R. | 登録日 | 2021-07-23 | 公開日 | 2021-09-08 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (2.71 Å) | 主引用文献 | Structural Study of Aavrh.10 Receptor and Antibody Interactions. J.Virol., 95, 2021
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5FZO
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![BU of 5fzo by Molmil](/molmil-images/mine/5fzo) | Crystal structure of the catalytic domain of human JmjD1C | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, MANGANESE (II) ION, ... | 著者 | Nowak, R, Talon, R, Krojer, T, Goubin, S, McDonough, M, Fairhead, M, Oppermann, U, Johansson, C. | 登録日 | 2016-03-15 | 公開日 | 2016-03-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Crystal Structure of the Catalytic Domain of Human Jmjd1C To be Published
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5JWY
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![BU of 5jwy by Molmil](/molmil-images/mine/5jwy) | Structure of lipid phosphate phosphatase PgpB complex with PE | 分子名称: | (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl tetradecanoate, Phosphatidylglycerophosphatase B | 著者 | Tong, S, Wang, M, Zheng, L. | 登録日 | 2016-05-12 | 公開日 | 2016-07-20 | 最終更新日 | 2019-11-27 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural Insight into Substrate Selection and Catalysis of Lipid Phosphate Phosphatase PgpB in the Cell Membrane. J.Biol.Chem., 291, 2016
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6TDO
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![BU of 6tdo by Molmil](/molmil-images/mine/6tdo) | Crystal structure of the disulfide engineered HLA-A0201 molecule in complex with one GM dipeptide in the A pocket. | 分子名称: | Beta-2-microglobulin, GLYCEROL, GLYCINE, ... | 著者 | Anjanappa, R, Garcia Alai, M, Springer, S, Meijers, R. | 登録日 | 2019-11-09 | 公開日 | 2020-03-25 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structures of peptide-free and partially loaded MHC class I molecules reveal mechanisms of peptide selection. Nat Commun, 11, 2020
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6W0L
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![BU of 6w0l by Molmil](/molmil-images/mine/6w0l) | Henipavirus W protein interacts with 14-3-3 to modulate host gene expression | 分子名称: | 14-3-3 protein sigma, CALCIUM ION, Phosphorylated W peptide | 著者 | Edwards, M, Hoad, M, Tsimbalyuk, S, Menicucci, A, Messaoudi, I, Forwood, J, Basler, C. | 登録日 | 2020-03-01 | 公開日 | 2020-04-22 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Henipavirus W Proteins Interact with 14-3-3 To Modulate Host Gene Expression. J.Virol., 94, 2020
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6TDQ
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![BU of 6tdq by Molmil](/molmil-images/mine/6tdq) | Crystal structure of the disulfide engineered HLA-A0201 molecule in complex with one GM dipeptide in the A pocket and one GM dipeptide in the F pocket. | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, CHLORIDE ION, ... | 著者 | Anjanappa, R, Garcia Alai, M, Springer, S, Meijers, R. | 登録日 | 2019-11-10 | 公開日 | 2020-03-25 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structures of peptide-free and partially loaded MHC class I molecules reveal mechanisms of peptide selection. Nat Commun, 11, 2020
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6GE0
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6TDS
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![BU of 6tds by Molmil](/molmil-images/mine/6tds) | Crystal structure of the disulfide engineered HLA-A0201 molecule without peptide bound after NaCl wash | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, CHLORIDE ION, ... | 著者 | Anjanappa, R, Garcia Alai, M, Springer, S, Meijers, R. | 登録日 | 2019-11-10 | 公開日 | 2020-03-25 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structures of peptide-free and partially loaded MHC class I molecules reveal mechanisms of peptide selection. Nat Commun, 11, 2020
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7LA4
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![BU of 7la4 by Molmil](/molmil-images/mine/7la4) | Integrin AlphaIIbBeta3-PT25-2 Complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Bush, M.W, Walz, T, Coller, B, Filizola, M, Spasic, A, Nesic, D, Li, J. | 登録日 | 2021-01-05 | 公開日 | 2022-01-12 | 最終更新日 | 2022-07-27 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Electron microscopy shows that binding of monoclonal antibody PT25-2 primes integrin alpha IIb beta 3 for ligand binding. Blood Adv, 5, 2021
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6CRG
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![BU of 6crg by Molmil](/molmil-images/mine/6crg) | Crystal Structure of Shp2 E76K GOF Mutant in complex with SHP099 | 分子名称: | 6-(4-azanyl-4-methyl-piperidin-1-yl)-3-[2,3-bis(chloranyl)phenyl]pyrazin-2-amine, GLYCEROL, SULFATE ION, ... | 著者 | Stams, T, Fodor, M. | 登録日 | 2018-03-17 | 公開日 | 2018-11-07 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Structural reorganization of SHP2 by oncogenic mutations and implications for oncoprotein resistance to allosteric inhibition. Nat Commun, 9, 2018
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6JLL
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![BU of 6jll by Molmil](/molmil-images/mine/6jll) | XFEL structure of cyanobacterial photosystem II (2F state, dataset1) | 分子名称: | 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ... | 著者 | Suga, M, Shen, J.R. | 登録日 | 2019-03-06 | 公開日 | 2019-10-16 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | An oxyl/oxo mechanism for oxygen-oxygen coupling in PSII revealed by an x-ray free-electron laser. Science, 366, 2019
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6TT2
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