7LA4

Integrin AlphaIIbBeta3-PT25-2 Complex

Summary for 7LA4

Entry DOI	10.2210/pdb7la4/pdb
EMDB information	23245
Descriptor	PT25-2 heavy chain, MAGNESIUM ION, PT25-2 light chain, ... (11 entities in total)
Functional Keywords	pt25-2, cell adhesion
Biological source	Mus musculus More
Total number of polymer chains	4
Total formula weight	249590.66
Authors	Bush, M.W.,Walz, T.,Coller, B.,Filizola, M.,Spasic, A.,Nesic, D.,Li, J. (deposition date: 2021-01-05, release date: 2022-01-12, Last modification date: 2022-07-27)
Primary citation	Nesic, D.,Bush, M.,Spasic, A.,Li, J.,Kamata, T.,Handa, M.,Filizola, M.,Walz, T.,Coller, B.S. Electron microscopy shows that binding of monoclonal antibody PT25-2 primes integrin alpha IIb beta 3 for ligand binding. Blood Adv, 5:1781-1790, 2021 Cited by PubMed: 33760023 DOI: 10.1182/bloodadvances.2020004166 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.3 Å)

Structure validation