5F8T

The crystal structure of human Plasma Kallikrein in complex with its peptide inhibitor pkalin-2

Replaces:  4ZJ5

Summary for 5F8T

• Entry DOI: 10.2210/pdb5f8t/pdb
• Related: 4ZJ4 4ZJ6
• Descriptor: Plasma kallikrein light chain, CYS-PRO-LYS-ARG-PHE-M70-ALA-LEU-PHE-CYS, SULFATE ION, ... (5 entities in total)
• Functional Keywords: peptide inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (Human); More
• Cellular location: Secreted: P03952
• Total number of polymer chains: 2
• Total formula weight: 28582.47

Authors

Xu, M.,Jiang, L.,Xu, P.,Luo, Z.,Andreasen, P.,Huang, M. (deposition date: 2015-12-09, release date: 2016-12-14, Last modification date: 2025-09-17)

• Primary citation: Xu, M.,Jiang, L.,Xu, P.,Luo, Z.,Andreasen, P.,Huang, M.; The crystal structure of human Plasma Kallikrein in complex with its peptide inhibitor pkalin-2; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.75 Å)