6TA5

OprM-MexA complex from the MexAB-OprM Pseudomonas aeruginosa whole assembly reconstituted in nanodiscs

Summary for 6TA5

Entry DOI	10.2210/pdb6ta5/pdb
Related	6TA6
EMDB information	10372
Descriptor	Outer membrane protein OprM, MexA family multidrug efflux RND transporter periplasmic adaptor subunit, Efflux pump membrane transporter (3 entities in total)
Functional Keywords	transporter, efflux, proton motive force, bacterial resistance, antimicrobial protein
Biological source	Pseudomonas aeruginosa More
Total number of polymer chains	12
Total formula weight	733105.16
Authors	Glavier, M.,Schoehn, G.,Taveau, J.C.,Phan, G.,Daury, L.,Lambert, O.,Broutin, I. (deposition date: 2019-10-29, release date: 2020-09-16, Last modification date: 2020-10-14)
Primary citation	Glavier, M.,Puvanendran, D.,Salvador, D.,Decossas, M.,Phan, G.,Garnier, C.,Frezza, E.,Cece, Q.,Schoehn, G.,Picard, M.,Taveau, J.C.,Daury, L.,Broutin, I.,Lambert, O. Antibiotic export by MexB multidrug efflux transporter is allosterically controlled by a MexA-OprM chaperone-like complex. Nat Commun, 11:4948-4948, 2020 Cited by PubMed: 33009415 DOI: 10.1038/s41467-020-18770-5 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.2 Å)

Structure validation