6TDO

Crystal structure of the disulfide engineered HLA-A0201 molecule in complex with one GM dipeptide in the A pocket.

Summary for 6TDO

• Entry DOI: 10.2210/pdb6tdo/pdb
• Descriptor: MHC class I antigen, Beta-2-microglobulin, GLYCINE, ... (6 entities in total)
• Functional Keywords: mhc class i molecule, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 44213.19

Authors

Anjanappa, R.,Garcia Alai, M.,Springer, S.,Meijers, R. (deposition date: 2019-11-09, release date: 2020-03-25, Last modification date: 2024-01-24)

• Primary citation: Anjanappa, R.,Garcia-Alai, M.,Kopicki, J.D.,Lockhauserbaumer, J.,Aboelmagd, M.,Hinrichs, J.,Nemtanu, I.M.,Uetrecht, C.,Zacharias, M.,Springer, S.,Meijers, R.; Structures of peptide-free and partially loaded MHC class I molecules reveal mechanisms of peptide selection.; Nat Commun, 11:1314-1314, 2020; PubMed: 32161266; DOI: 10.1038/s41467-020-14862-4

Experimental method

X-RAY DIFFRACTION (1.65 Å)