6TDO
Crystal structure of the disulfide engineered HLA-A0201 molecule in complex with one GM dipeptide in the A pocket.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | MHC class I antigen | polymer | 276 | 31925.4 | 1 | UniProt (F6IQS1) Pfam (PF00129) Pfam (PF07654) | Homo sapiens (Human) | |
| 2 | B (B) | Beta-2-microglobulin | polymer | 100 | 11879.4 | 1 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (Human) | |
| 3 | C (A) | GLYCINE | non-polymer | 75.1 | 1 | Chemie (GLY) | |||
| 4 | D (A) | METHIONINE | non-polymer | 149.2 | 1 | Chemie (MET) | |||
| 5 | E, F (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 6 | G, H (A, B) | water | water | 18.0 | 522 | Chemie (HOH) |
Sequence modifications
A: 0 - 275 (UniProt: F6IQS1)
B: 1 - 99 (UniProt: P61769)
| PDB | External Database | Details |
|---|---|---|
| Cys 84 | Tyr 108 | conflict |
| Cys 139 | Ala 163 | conflict |
| Val 245 | Ala 269 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 43804.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 408.5 | |
| All* | Total formula weight | 44213.2 |
