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6TDS

Crystal structure of the disulfide engineered HLA-A0201 molecule without peptide bound after NaCl wash

Summary for 6TDS
Entry DOI10.2210/pdb6tds/pdb
DescriptorMHC class I antigen, Beta-2-microglobulin, 1,2-ETHANEDIOL, ... (6 entities in total)
Functional Keywordsmhc class i molecule, immune system
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains4
Total formula weight88672.39
Authors
Anjanappa, R.,Garcia Alai, M.,Springer, S.,Meijers, R. (deposition date: 2019-11-10, release date: 2020-03-25, Last modification date: 2024-01-24)
Primary citationAnjanappa, R.,Garcia-Alai, M.,Kopicki, J.D.,Lockhauserbaumer, J.,Aboelmagd, M.,Hinrichs, J.,Nemtanu, I.M.,Uetrecht, C.,Zacharias, M.,Springer, S.,Meijers, R.
Structures of peptide-free and partially loaded MHC class I molecules reveal mechanisms of peptide selection.
Nat Commun, 11:1314-1314, 2020
Cited by
PubMed: 32161266
DOI: 10.1038/s41467-020-14862-4
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.7 Å)
Structure validation

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