6LAV
 
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6LIK
 | | Crystal Structure of Lectin from Pleurotus ostreatus in complex with Galactose | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ... | | Authors: | Vajravijayan, S, Pletnev, S, Luo, Z, Iqbal, S, Nandhagopal, N, Gunasekaran, K. | | Deposit date: | 2019-12-11 | | Release date: | 2020-08-05 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystallographic and calorimetric analysis on Pleurotus ostreatus lectin and its sugar complexes - promiscuous binding driven by geometry.
Int.J.Biol.Macromol., 152, 2020
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6LI7
 | | Crystal Structure of Lectin from Pleurotus ostreatus in complex with GalNAc | | Descriptor: | 2-acetamido-2-deoxy-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | Authors: | Vajravijayan, S, Pletnev, S, Luo, Z, Ankur, T, Gunasekaran, K, Nandhagopal, N. | | Deposit date: | 2019-12-10 | | Release date: | 2020-08-05 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.098 Å) | | Cite: | Crystallographic and calorimetric analysis on Pleurotus ostreatus lectin and its sugar complexes - promiscuous binding driven by geometry.
Int.J.Biol.Macromol., 152, 2020
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8HTW
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7LD0
 | | Cryo-EM structure of ligand-free Human SARM1 | | Descriptor: | NAD(+) hydrolase SARM1 | | Authors: | Nanson, J.D, Gu, W, Luo, Z, Jia, X, Landsberg, M.J, Kobe, B, Ve, T. | | Deposit date: | 2021-01-12 | | Release date: | 2021-03-10 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | SARM1 is a metabolic sensor activated by an increased NMN/NAD + ratio to trigger axon degeneration.
Neuron, 109, 2021
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7LCY
 | | Crystal structure of the ligand-free ARM domain from Drosophila SARM1 | | Descriptor: | Isoform B of NAD(+) hydrolase sarm1 | | Authors: | Gu, W, Nanson, J.D, Luo, Z, McGuinness, H.Y, Manik, M.K, Jia, X, Ve, T, Kobe, B. | | Deposit date: | 2021-01-12 | | Release date: | 2021-03-10 | | Last modified: | 2021-04-21 | | Method: | X-RAY DIFFRACTION (3.35 Å) | | Cite: | SARM1 is a metabolic sensor activated by an increased NMN/NAD + ratio to trigger axon degeneration.
Neuron, 109, 2021
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7LCZ
 | | Crystal structure of the ARM domain from Drosophila SARM1 in complex with NMN | | Descriptor: | 1,2-ETHANEDIOL, BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, Isoform B of NAD(+) hydrolase sarm1, ... | | Authors: | Gu, W, Nanson, J.D, Luo, Z, Jia, X, Manik, M.K, Ve, T, Kobe, B. | | Deposit date: | 2021-01-12 | | Release date: | 2021-03-10 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | SARM1 is a metabolic sensor activated by an increased NMN/NAD + ratio to trigger axon degeneration.
Neuron, 109, 2021
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7LVO
 | | Cryptococcus neoformans GAR synthetase | | Descriptor: | 1,2-ETHANEDIOL, phosphoribosyl-glycinamide (GAR) synthetase | | Authors: | Chua, S.M.H, Luo, Z, Lim, B.Y.J, Kobe, B, Fraser, J.A. | | Deposit date: | 2021-02-26 | | Release date: | 2021-08-25 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural features of Cryptococcus neoformans bifunctional GAR/AIR synthetase may present novel antifungal drug targets.
J.Biol.Chem., 297, 2021
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7MGQ
 | | AICAR transformylase/IMP cyclohydrolase (ATIC) is essential for de novo purine biosynthesis and infection by Cryptococcus neoformans | | Descriptor: | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase, MAGNESIUM ION | | Authors: | Wizrah, M.S, Chua, S.M.H, Luo, Z, Manik, M.K, Pan, M, Whyte, J.M, Robertson, A.B, Kappler, U, Kobe, B, Fraser, J.A. | | Deposit date: | 2021-04-13 | | Release date: | 2022-04-20 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.67 Å) | | Cite: | AICAR transformylase/IMP cyclohydrolase (ATIC) is essential for de novo purine biosynthesis and infection by Cryptococcus neoformans.
J.Biol.Chem., 298, 2022
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7M6K
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7LVP
 | | Cryptococcus neoformans AIR synthetase | | Descriptor: | 1,2-ETHANEDIOL, AIR synthase, GLYCINE, ... | | Authors: | Chua, S.M.H, Luo, Z, Lim, B.Y.J, Kobe, B, Fraser, J.A. | | Deposit date: | 2021-02-26 | | Release date: | 2021-08-25 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.24 Å) | | Cite: | Structural features of Cryptococcus neoformans bifunctional GAR/AIR synthetase may present novel antifungal drug targets.
J.Biol.Chem., 297, 2021
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7T4Z
 | | Crystal structure of the molybdate-binding periplasmic protein ModA from the bacteria Pseudomonsa aeruginosa in ligand-free form | | Descriptor: | AMMONIUM ION, GLYCEROL, Molybdate-binding periplasmic protein, ... | | Authors: | Ngu, D.H.Y, Luo, Z, Lim, B.Y.J, Kobe, B. | | Deposit date: | 2021-12-10 | | Release date: | 2022-05-04 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.78 Å) | | Cite: | The Impact of Chromate on Pseudomonas aeruginosa Molybdenum Homeostasis.
Front Microbiol, 13, 2022
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7T50
 | | Crystal structure of the molybdate-binding periplasmic protein ModA from the bacteria Pseudomonsa aeruginosa in chromate-bound form | | Descriptor: | AMMONIUM ION, Chromate, GLYCEROL, ... | | Authors: | Ngu, D.H.Y, Luo, Z, Lim, B.Y.J, Kobe, B. | | Deposit date: | 2021-12-11 | | Release date: | 2022-05-04 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | The Impact of Chromate on Pseudomonas aeruginosa Molybdenum Homeostasis.
Front Microbiol, 13, 2022
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7T51
 | | Crystal structure of the molybdate-binding periplasmic protein ModA from the bacteria Pseudomonsa aeruginosa in molybdate-bound form | | Descriptor: | AMMONIUM ION, GLYCEROL, MOLYBDATE ION, ... | | Authors: | Ngu, D.H.Y, Luo, Z, Lim, B.Y.J, Kobe, B. | | Deposit date: | 2021-12-11 | | Release date: | 2022-05-04 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | The Impact of Chromate on Pseudomonas aeruginosa Molybdenum Homeostasis.
Front Microbiol, 13, 2022
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7T5A
 | | Crystal structure of the molybdate-binding periplasmic protein ModA from the bacteria Pseudomonsa aeruginosa in tungstate-bound form | | Descriptor: | AMMONIUM ION, Molybdate-binding periplasmic protein ModA, TUNGSTATE(VI)ION | | Authors: | Ngu, D.H.Y, Luo, Z, Lim, B.Y.J, Kobe, B. | | Deposit date: | 2021-12-11 | | Release date: | 2022-05-04 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.16 Å) | | Cite: | The Impact of Chromate on Pseudomonas aeruginosa Molybdenum Homeostasis.
Front Microbiol, 13, 2022
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4K2C
 | | HSA Ligand Free | | Descriptor: | Serum albumin | | Authors: | Wang, Y, Luo, Z, Shi, X, Huang, M. | | Deposit date: | 2013-04-08 | | Release date: | 2013-05-01 | | Last modified: | 2018-02-21 | | Method: | X-RAY DIFFRACTION (3.23 Å) | | Cite: | Structural mechanism of ring-opening reaction of glucose by human serum albumin.
J. Biol. Chem., 288, 2013
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4IW2
 | | HSA-glucose complex | | Descriptor: | D-glucose, PHOSPHATE ION, Serum albumin, ... | | Authors: | Wang, Y, Yu, H, Shi, X, Luo, Z, Huang, M. | | Deposit date: | 2013-01-23 | | Release date: | 2013-04-24 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.41 Å) | | Cite: | Structural mechanism of ring-opening reaction of glucose by human serum albumin
J.Biol.Chem., 288, 2013
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4QTH
 | | Crystal structure of anti-uPAR Fab 8B12 | | Descriptor: | anti-uPAR antibody, heavy chain, light chain | | Authors: | Zhao, B, Yuan, C, Luo, Z, Huang, M. | | Deposit date: | 2014-07-08 | | Release date: | 2015-02-25 | | Last modified: | 2022-08-24 | | Method: | X-RAY DIFFRACTION (2.17 Å) | | Cite: | Stabilizing a flexible interdomain hinge region harboring the SMB binding site drives uPAR into its closed conformation.
J.Mol.Biol., 427, 2015
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4QTI
 | | Crystal structure of human uPAR in complex with anti-uPAR Fab 8B12 | | Descriptor: | Urokinase plasminogen activator surface receptor, anti-uPAR antibody, heavy chain, ... | | Authors: | Zhao, B, Yuan, C, Luo, Z, Huang, M. | | Deposit date: | 2014-07-08 | | Release date: | 2015-02-25 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Stabilizing a flexible interdomain hinge region harboring the SMB binding site drives uPAR into its closed conformation.
J.Mol.Biol., 427, 2015
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3TDL
 | | Structure of human serum albumin in complex with DAUDA | | Descriptor: | 11-({[5-(dimethylamino)naphthalen-1-yl]sulfonyl}amino)undecanoic acid, MYRISTIC ACID, Serum albumin | | Authors: | Wang, Y, Luo, Z, Shi, X, Wang, H, Nie, L. | | Deposit date: | 2011-08-11 | | Release date: | 2012-06-27 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | A fluorescent fatty acid probe, DAUDA, selectively displaces two myristates bound in human serum albumin
Protein Sci., 20, 2011
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5ZM6
 | | Crystal structure of ORP1-ORD in complex with PI(4,5)P2 | | Descriptor: | ACETATE ION, Oxysterol-binding protein-related protein 1, [(2~{S})-1-octadecanoyloxy-3-[oxidanyl-[(1~{R},2~{R},3~{S},4~{S},5~{S},6~{S})-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propan-2-yl] icosa-5,8,11,14-tetraenoate | | Authors: | Dong, J, Wang, J, Luo, Z, Wu, J.W. | | Deposit date: | 2018-04-01 | | Release date: | 2019-02-27 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Allosteric enhancement of ORP1-mediated cholesterol transport by PI(4,5)P2/PI(3,4)P2.
Nat Commun, 10, 2019
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5F8T
 | | The crystal structure of human Plasma Kallikrein in complex with its peptide inhibitor pkalin-2 | | Descriptor: | CYS-PRO-LYS-ARG-PHE-M70-ALA-LEU-PHE-CYS, Plasma kallikrein light chain, SULFATE ION, ... | | Authors: | Xu, M, Jiang, L, Xu, P, Luo, Z, Andreasen, P, Huang, M. | | Deposit date: | 2015-12-09 | | Release date: | 2016-12-14 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | The crystal structure of human Plasma Kallikrein in complex with its peptide inhibitor pkalin-2
To Be Published
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6KJ3
 | | 120kV MicroED structure of FUS (37-42) SYSGYS solved from merged datasets at 0.60 A | | Descriptor: | RNA-binding protein FUS | | Authors: | Zhou, H, Luo, F, Luo, Z, Li, D, Liu, C, Li, X. | | Deposit date: | 2019-07-20 | | Release date: | 2019-10-02 | | Last modified: | 2024-03-27 | | Method: | ELECTRON CRYSTALLOGRAPHY (0.6 Å) | | Cite: | Programming Conventional Electron Microscopes for Solving Ultrahigh-Resolution Structures of Small and Macro-Molecules.
Anal.Chem., 91, 2019
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6KJ4
 | | 120kV MicroED structure of FUS (37-42) SYSGYS solved from single crystal at 0.65 A | | Descriptor: | RNA-binding protein FUS | | Authors: | Zhou, H, Luo, F, Luo, Z, Li, D, Liu, C, Li, X. | | Deposit date: | 2019-07-20 | | Release date: | 2019-10-02 | | Last modified: | 2024-03-27 | | Method: | ELECTRON CRYSTALLOGRAPHY (0.65 Å) | | Cite: | Programming Conventional Electron Microscopes for Solving Ultrahigh-Resolution Structures of Small and Macro-Molecules.
Anal.Chem., 91, 2019
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6KJ2
 | | 200kV MicroED structure of FUS (37-42) SYSGYS solved from single crystal at 0.67 A | | Descriptor: | RNA-binding protein FUS | | Authors: | Zhou, H, Luo, F, Luo, Z, Li, D, Liu, C, Li, X. | | Deposit date: | 2019-07-20 | | Release date: | 2019-10-02 | | Last modified: | 2024-03-27 | | Method: | ELECTRON CRYSTALLOGRAPHY (0.67 Å) | | Cite: | Programming Conventional Electron Microscopes for Solving Ultrahigh-Resolution Structures of Small and Macro-Molecules.
Anal.Chem., 91, 2019
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