4QTH
Crystal structure of anti-uPAR Fab 8B12
Summary for 4QTH
Entry DOI | 10.2210/pdb4qth/pdb |
Related | 4QTI |
Descriptor | anti-uPAR antibody, heavy chain, anti-uPAR antibody, light chain (3 entities in total) |
Functional Keywords | antibody, immune system |
Biological source | Mus musculus (mouse) More |
Total number of polymer chains | 4 |
Total formula weight | 95351.60 |
Authors | |
Primary citation | Zhao, B.,Gandhi, S.,Yuan, C.,Luo, Z.,Li, R.,Gardsvoll, H.,de Lorenzi, V.,Sidenius, N.,Huang, M.,Ploug, M. Stabilizing a flexible interdomain hinge region harboring the SMB binding site drives uPAR into its closed conformation. J.Mol.Biol., 427:1389-1403, 2015 Cited by PubMed: 25659907DOI: 10.1016/j.jmb.2015.01.022 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.17 Å) |
Structure validation
Download full validation report