7TR4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7tr4 by Molmil](/molmil-images/mine/7tr4) | MA2-MART1-HLAA0201 | 分子名称: | Beta-2-microglobulin, GLYCEROL, HLA-A*02:01, ... | 著者 | Yang, X, Jude, K.M, Garcia, K.C. | 登録日 | 2022-01-27 | 公開日 | 2022-11-23 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Facile repurposing of peptide-MHC-restricted antibodies for cancer immunotherapy. Nat.Biotechnol., 41, 2023
|
|
7U7N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7u7n by Molmil](/molmil-images/mine/7u7n) | IL-27 quaternary receptor signaling complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-27 receptor subunit alpha, ... | 著者 | Caveney, N.A, Glassman, C.R, Jude, K.M, Tsutsumi, N, Garcia, K.C. | 登録日 | 2022-03-07 | 公開日 | 2022-05-25 | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | 主引用文献 | Structure of the IL-27 quaternary receptor signaling complex. Elife, 11, 2022
|
|
7UWL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7uwl by Molmil](/molmil-images/mine/7uwl) | Structure of the IL-25-IL-17RB-IL-17RA ternary complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-17 receptor A, ... | 著者 | Wilson, S.C, Caveney, N.A, Jude, K.M, Garcia, K.C. | 登録日 | 2022-05-03 | 公開日 | 2022-07-27 | 最終更新日 | 2022-09-28 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Organizing structural principles of the IL-17 ligand-receptor axis. Nature, 609, 2022
|
|
7UWM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7uwm by Molmil](/molmil-images/mine/7uwm) | Structure of the IL-17A-IL-17RA binary complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-17 receptor A, ... | 著者 | Wilson, S.C, Caveney, N.A, Jude, K.M, Garcia, K.C. | 登録日 | 2022-05-03 | 公開日 | 2022-07-27 | 最終更新日 | 2022-09-28 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Organizing structural principles of the IL-17 ligand-receptor axis. Nature, 609, 2022
|
|
7UWK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7uwk by Molmil](/molmil-images/mine/7uwk) | Structure of the higher-order IL-25-IL-17RB complex | 分子名称: | Interleukin-17 receptor B, Interleukin-25 | 著者 | Wilson, S.C, Caveney, N.A, Jude, K.M, Garcia, K.C. | 登録日 | 2022-05-03 | 公開日 | 2022-07-27 | 最終更新日 | 2022-09-28 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Organizing structural principles of the IL-17 ligand-receptor axis. Nature, 609, 2022
|
|
7UWJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7uwj by Molmil](/molmil-images/mine/7uwj) | Structure of the homodimeric IL-25-IL-17RB binary complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-17 receptor B, Interleukin-25 | 著者 | Wilson, S.C, Caveney, N.A, Jude, K.M, Garcia, K.C. | 登録日 | 2022-05-03 | 公開日 | 2022-07-27 | 最終更新日 | 2022-09-28 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Organizing structural principles of the IL-17 ligand-receptor axis. Nature, 609, 2022
|
|
7UWN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7uwn by Molmil](/molmil-images/mine/7uwn) | Structure of the IL-17A-IL-17RA-IL-17RC ternary complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-17 receptor A, ... | 著者 | Wilson, S.C, Caveney, N.A, Jude, K.M, Garcia, K.C. | 登録日 | 2022-05-03 | 公開日 | 2022-07-27 | 最終更新日 | 2022-09-28 | 実験手法 | ELECTRON MICROSCOPY (3.01 Å) | 主引用文献 | Organizing structural principles of the IL-17 ligand-receptor axis. Nature, 609, 2022
|
|
8CTG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ctg by Molmil](/molmil-images/mine/8ctg) | Extracellular architecture of an engineered canonical Wnt signaling ternary complex | 分子名称: | Frizzled-8, Low-density lipoprotein receptor-related protein 6, PALMITOLEIC ACID, ... | 著者 | Tsutsumi, N, Jude, K.M, Garcia, K.C. | 登録日 | 2022-05-14 | 公開日 | 2023-03-15 | 最終更新日 | 2023-03-22 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structure of the Wnt-Frizzled-LRP6 initiation complex reveals the basis for coreceptor discrimination. Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
8ENT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ent by Molmil](/molmil-images/mine/8ent) | Interleukin-21 signaling complex with IL-21R and IL-2Rg | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Abhiraman, G.C, Jude, K.M, Garcia, K.C. | 登録日 | 2022-09-30 | 公開日 | 2023-06-28 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.83 Å) | 主引用文献 | A structural blueprint for interleukin-21 signal modulation. Cell Rep, 42, 2023
|
|
8G04
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8g04 by Molmil](/molmil-images/mine/8g04) | Structure of signaling thrombopoietin-MPL receptor complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Thrombopoietin, Thrombopoietin receptor, ... | 著者 | Tsutsumi, N, Jude, K.M, Gati, C, Garcia, K.C. | 登録日 | 2023-01-31 | 公開日 | 2023-08-30 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structure of the thrombopoietin-MPL receptor complex is a blueprint for biasing hematopoiesis. Cell, 186, 2023
|
|
7N2O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7n2o by Molmil](/molmil-images/mine/7n2o) | AS4.2-YEIH-HLA*B27 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, GLYCEROL, ... | 著者 | Yang, X, Jude, K.M, Garcia, K.C. | 登録日 | 2021-05-29 | 公開日 | 2022-12-07 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides. Nature, 612, 2022
|
|
7N2Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7n2q by Molmil](/molmil-images/mine/7n2q) | AS4.3-YEIH-HLA*B27 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, AS4.3 T cell receptor alpha chain, AS4.3 T cell receptor beta chain, ... | 著者 | Yang, X, Jude, K.M, Garcia, K.C. | 登録日 | 2021-05-29 | 公開日 | 2022-12-07 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides. Nature, 612, 2022
|
|
7N2S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7n2s by Molmil](/molmil-images/mine/7n2s) | AS3.1-PRPF3-HLA*B27 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, GLYCEROL, ... | 著者 | Yang, X, Jude, K.M, Garcia, K.C. | 登録日 | 2021-05-29 | 公開日 | 2022-12-07 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | 主引用文献 | Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides. Nature, 612, 2022
|
|
7N2R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7n2r by Molmil](/molmil-images/mine/7n2r) | AS4.3-PRPF3-HLA*B27 | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, AS4.3 T cell receptor alpha chain, ... | 著者 | Yang, X, Jude, K.M, Garcia, K.C. | 登録日 | 2021-05-29 | 公開日 | 2022-12-07 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides. Nature, 612, 2022
|
|
7N2N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7n2n by Molmil](/molmil-images/mine/7n2n) | TCR-antigen complex AS4.2-PRPF3-HLA*B27 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, GLYCEROL, ... | 著者 | Yang, X, Jude, K.M, Garcia, K.C. | 登録日 | 2021-05-29 | 公開日 | 2022-12-07 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides. Nature, 612, 2022
|
|
7N2P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7n2p by Molmil](/molmil-images/mine/7n2p) | AS4.3-RNASEH2b-HLA*B27 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, AS4.3 T cell receptor alpha chain, AS4.3 T cell receptor beta chain, ... | 著者 | Yang, X, Jude, K.M, Garcia, K.C. | 登録日 | 2021-05-29 | 公開日 | 2022-12-07 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides. Nature, 612, 2022
|
|
5E4E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5e4e by Molmil](/molmil-images/mine/5e4e) | Engineered Interleukin-13 bound to receptor | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-13, Interleukin-13 receptor subunit alpha-1, ... | 著者 | Moraga, I, Thomas, C, Jude, K.M, Garcia, K.C. | 登録日 | 2015-10-05 | 公開日 | 2015-12-02 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Instructive roles for cytokine-receptor binding parameters in determining signaling and functional potency. Sci.Signal., 8, 2015
|
|
7RKM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7rkm by Molmil](/molmil-images/mine/7rkm) | Structure of CX3CL1-US28-Gi-scFv16 in C-state | 分子名称: | Antibody fragment scFv16, CHOLESTEROL, Fractalkine, ... | 著者 | Tsutsumi, N, Qu, Q, Jude, K.M, Skiniotis, G, Garcia, K.C. | 登録日 | 2021-07-22 | 公開日 | 2022-01-26 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Atypical structural snapshots of human cytomegalovirus GPCR interactions with host G proteins Sci Adv, 8, 2022
|
|
7RKY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7rky by Molmil](/molmil-images/mine/7rky) | Binding mode of US27-Gi-scFv16 in OCL-state | 分子名称: | Antibody fragment scFv16, G-protein coupled receptor homolog US27, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Tsutsumi, N, Jude, K.M, Garcia, K.C. | 登録日 | 2021-07-22 | 公開日 | 2022-01-26 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Atypical structural snapshots of human cytomegalovirus GPCR interactions with host G proteins Sci Adv, 8, 2022
|
|
7RKN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7rkn by Molmil](/molmil-images/mine/7rkn) | Structure of CX3CL1-US28-Gi-scFv16 in OC-state | 分子名称: | Antibody fragment scFv16, Fractalkine, G-protein coupled receptor homolog US28, ... | 著者 | Tsutsumi, N, Qu, Q, Jude, K.M, Skiniotis, G, Garcia, K.C. | 登録日 | 2021-07-22 | 公開日 | 2022-01-26 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Atypical structural snapshots of human cytomegalovirus GPCR interactions with host G proteins Sci Adv, 8, 2022
|
|
7RKX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7rkx by Molmil](/molmil-images/mine/7rkx) | Structure of US27-Gi-scFv16 in CL-state | 分子名称: | Antibody fragment scFv16, G-protein coupled receptor homolog US27, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Tsutsumi, N, Jude, K.M, Garcia, K.C. | 登録日 | 2021-07-22 | 公開日 | 2022-01-26 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Atypical structural snapshots of human cytomegalovirus GPCR interactions with host G proteins Sci Adv, 8, 2022
|
|
7R86
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7r86 by Molmil](/molmil-images/mine/7r86) | Structure of mouse BAI1 (ADGRB1) in complex with mouse Nogo receptor (RTN4R) | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-AMINOBENZOIC ACID, ... | 著者 | Miao, Y, Jude, K.M, Garcia, K.C. | 登録日 | 2021-06-26 | 公開日 | 2021-11-10 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | RTN4/NoGo-receptor binding to BAI adhesion-GPCRs regulates neuronal development. Cell, 184, 2021
|
|
7R85
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7r85 by Molmil](/molmil-images/mine/7r85) | |
7R84
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7r84 by Molmil](/molmil-images/mine/7r84) | |
7T6F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7t6f by Molmil](/molmil-images/mine/7t6f) | Structure of active Janus Kinase (JAK) dimer complexed with cytokine receptor intracellular domain | 分子名称: | ADENOSINE, ADENOSINE-5'-DIPHOSPHATE, Interferon lambda receptor 1, ... | 著者 | Glassman, C.R, Tsutsumi, N, Jude, K.M, Garcia, K.C. | 登録日 | 2021-12-13 | 公開日 | 2022-03-16 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structure of a Janus kinase cytokine receptor complex reveals the basis for dimeric activation. Science, 376, 2022
|
|