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PDB: 104 件

7TR4
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MA2-MART1-HLAA0201
分子名称: Beta-2-microglobulin, GLYCEROL, HLA-A*02:01, ...
著者Yang, X, Jude, K.M, Garcia, K.C.
登録日2022-01-27
公開日2022-11-23
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Facile repurposing of peptide-MHC-restricted antibodies for cancer immunotherapy.
Nat.Biotechnol., 41, 2023
7U7N
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IL-27 quaternary receptor signaling complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-27 receptor subunit alpha, ...
著者Caveney, N.A, Glassman, C.R, Jude, K.M, Tsutsumi, N, Garcia, K.C.
登録日2022-03-07
公開日2022-05-25
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Structure of the IL-27 quaternary receptor signaling complex.
Elife, 11, 2022
7UWL
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Structure of the IL-25-IL-17RB-IL-17RA ternary complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-17 receptor A, ...
著者Wilson, S.C, Caveney, N.A, Jude, K.M, Garcia, K.C.
登録日2022-05-03
公開日2022-07-27
最終更新日2022-09-28
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Organizing structural principles of the IL-17 ligand-receptor axis.
Nature, 609, 2022
7UWM
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Structure of the IL-17A-IL-17RA binary complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-17 receptor A, ...
著者Wilson, S.C, Caveney, N.A, Jude, K.M, Garcia, K.C.
登録日2022-05-03
公開日2022-07-27
最終更新日2022-09-28
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Organizing structural principles of the IL-17 ligand-receptor axis.
Nature, 609, 2022
7UWK
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Structure of the higher-order IL-25-IL-17RB complex
分子名称: Interleukin-17 receptor B, Interleukin-25
著者Wilson, S.C, Caveney, N.A, Jude, K.M, Garcia, K.C.
登録日2022-05-03
公開日2022-07-27
最終更新日2022-09-28
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Organizing structural principles of the IL-17 ligand-receptor axis.
Nature, 609, 2022
7UWJ
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Structure of the homodimeric IL-25-IL-17RB binary complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-17 receptor B, Interleukin-25
著者Wilson, S.C, Caveney, N.A, Jude, K.M, Garcia, K.C.
登録日2022-05-03
公開日2022-07-27
最終更新日2022-09-28
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Organizing structural principles of the IL-17 ligand-receptor axis.
Nature, 609, 2022
7UWN
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Structure of the IL-17A-IL-17RA-IL-17RC ternary complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-17 receptor A, ...
著者Wilson, S.C, Caveney, N.A, Jude, K.M, Garcia, K.C.
登録日2022-05-03
公開日2022-07-27
最終更新日2022-09-28
実験手法ELECTRON MICROSCOPY (3.01 Å)
主引用文献Organizing structural principles of the IL-17 ligand-receptor axis.
Nature, 609, 2022
8CTG
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Extracellular architecture of an engineered canonical Wnt signaling ternary complex
分子名称: Frizzled-8, Low-density lipoprotein receptor-related protein 6, PALMITOLEIC ACID, ...
著者Tsutsumi, N, Jude, K.M, Garcia, K.C.
登録日2022-05-14
公開日2023-03-15
最終更新日2023-03-22
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure of the Wnt-Frizzled-LRP6 initiation complex reveals the basis for coreceptor discrimination.
Proc.Natl.Acad.Sci.USA, 120, 2023
8ENT
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Interleukin-21 signaling complex with IL-21R and IL-2Rg
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Abhiraman, G.C, Jude, K.M, Garcia, K.C.
登録日2022-09-30
公開日2023-06-28
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.83 Å)
主引用文献A structural blueprint for interleukin-21 signal modulation.
Cell Rep, 42, 2023
8G04
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Structure of signaling thrombopoietin-MPL receptor complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Thrombopoietin, Thrombopoietin receptor, ...
著者Tsutsumi, N, Jude, K.M, Gati, C, Garcia, K.C.
登録日2023-01-31
公開日2023-08-30
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structure of the thrombopoietin-MPL receptor complex is a blueprint for biasing hematopoiesis.
Cell, 186, 2023
7N2O
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AS4.2-YEIH-HLA*B27
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, GLYCEROL, ...
著者Yang, X, Jude, K.M, Garcia, K.C.
登録日2021-05-29
公開日2022-12-07
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides.
Nature, 612, 2022
7N2Q
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AS4.3-YEIH-HLA*B27
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, AS4.3 T cell receptor alpha chain, AS4.3 T cell receptor beta chain, ...
著者Yang, X, Jude, K.M, Garcia, K.C.
登録日2021-05-29
公開日2022-12-07
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides.
Nature, 612, 2022
7N2S
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AS3.1-PRPF3-HLA*B27
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, GLYCEROL, ...
著者Yang, X, Jude, K.M, Garcia, K.C.
登録日2021-05-29
公開日2022-12-07
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides.
Nature, 612, 2022
7N2R
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AS4.3-PRPF3-HLA*B27
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, AS4.3 T cell receptor alpha chain, ...
著者Yang, X, Jude, K.M, Garcia, K.C.
登録日2021-05-29
公開日2022-12-07
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides.
Nature, 612, 2022
7N2N
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TCR-antigen complex AS4.2-PRPF3-HLA*B27
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, GLYCEROL, ...
著者Yang, X, Jude, K.M, Garcia, K.C.
登録日2021-05-29
公開日2022-12-07
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides.
Nature, 612, 2022
7N2P
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BU of 7n2p by Molmil
AS4.3-RNASEH2b-HLA*B27
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, AS4.3 T cell receptor alpha chain, AS4.3 T cell receptor beta chain, ...
著者Yang, X, Jude, K.M, Garcia, K.C.
登録日2021-05-29
公開日2022-12-07
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides.
Nature, 612, 2022
5E4E
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BU of 5e4e by Molmil
Engineered Interleukin-13 bound to receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-13, Interleukin-13 receptor subunit alpha-1, ...
著者Moraga, I, Thomas, C, Jude, K.M, Garcia, K.C.
登録日2015-10-05
公開日2015-12-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Instructive roles for cytokine-receptor binding parameters in determining signaling and functional potency.
Sci.Signal., 8, 2015
7RKM
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BU of 7rkm by Molmil
Structure of CX3CL1-US28-Gi-scFv16 in C-state
分子名称: Antibody fragment scFv16, CHOLESTEROL, Fractalkine, ...
著者Tsutsumi, N, Qu, Q, Jude, K.M, Skiniotis, G, Garcia, K.C.
登録日2021-07-22
公開日2022-01-26
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Atypical structural snapshots of human cytomegalovirus GPCR interactions with host G proteins
Sci Adv, 8, 2022
7RKY
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Binding mode of US27-Gi-scFv16 in OCL-state
分子名称: Antibody fragment scFv16, G-protein coupled receptor homolog US27, GUANOSINE-5'-DIPHOSPHATE, ...
著者Tsutsumi, N, Jude, K.M, Garcia, K.C.
登録日2021-07-22
公開日2022-01-26
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Atypical structural snapshots of human cytomegalovirus GPCR interactions with host G proteins
Sci Adv, 8, 2022
7RKN
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Structure of CX3CL1-US28-Gi-scFv16 in OC-state
分子名称: Antibody fragment scFv16, Fractalkine, G-protein coupled receptor homolog US28, ...
著者Tsutsumi, N, Qu, Q, Jude, K.M, Skiniotis, G, Garcia, K.C.
登録日2021-07-22
公開日2022-01-26
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Atypical structural snapshots of human cytomegalovirus GPCR interactions with host G proteins
Sci Adv, 8, 2022
7RKX
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Structure of US27-Gi-scFv16 in CL-state
分子名称: Antibody fragment scFv16, G-protein coupled receptor homolog US27, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Tsutsumi, N, Jude, K.M, Garcia, K.C.
登録日2021-07-22
公開日2022-01-26
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Atypical structural snapshots of human cytomegalovirus GPCR interactions with host G proteins
Sci Adv, 8, 2022
7R86
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Structure of mouse BAI1 (ADGRB1) in complex with mouse Nogo receptor (RTN4R)
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-AMINOBENZOIC ACID, ...
著者Miao, Y, Jude, K.M, Garcia, K.C.
登録日2021-06-26
公開日2021-11-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献RTN4/NoGo-receptor binding to BAI adhesion-GPCRs regulates neuronal development.
Cell, 184, 2021
7R85
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Structure of mouse Bai1 (ADGRB1) TSR3 domain
分子名称: Vasculostatin-120, alpha-D-mannopyranose, beta-D-glucopyranose-(1-3)-alpha-L-fucopyranose
著者Miao, Y, Jude, K.M, Garcia, K.C.
登録日2021-06-26
公開日2021-11-10
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献RTN4/NoGo-receptor binding to BAI adhesion-GPCRs regulates neuronal development.
Cell, 184, 2021
7R84
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Structure of mouse BAI1 (ADGRB1) TSR3 domain in P21 space group
分子名称: Vasculostatin-120, alpha-D-mannopyranose, beta-D-glucopyranose-(1-3)-alpha-L-fucopyranose
著者Miao, Y, Jude, K.M, Garcia, K.C.
登録日2021-06-26
公開日2021-11-10
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.336 Å)
主引用文献RTN4/NoGo-receptor binding to BAI adhesion-GPCRs regulates neuronal development.
Cell, 184, 2021
7T6F
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Structure of active Janus Kinase (JAK) dimer complexed with cytokine receptor intracellular domain
分子名称: ADENOSINE, ADENOSINE-5'-DIPHOSPHATE, Interferon lambda receptor 1, ...
著者Glassman, C.R, Tsutsumi, N, Jude, K.M, Garcia, K.C.
登録日2021-12-13
公開日2022-03-16
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structure of a Janus kinase cytokine receptor complex reveals the basis for dimeric activation.
Science, 376, 2022

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