5E4E

Engineered Interleukin-13 bound to receptor

Summary for 5E4E

• Entry DOI: 10.2210/pdb5e4e/pdb
• Descriptor: Interleukin-13, Interleukin-4 receptor subunit alpha, Interleukin-13 receptor subunit alpha-1, ... (5 entities in total)
• Functional Keywords: agonist-receptor complex, protein engineering, signaling protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 73361.29

Authors

Moraga, I.,Thomas, C.,Jude, K.M.,Garcia, K.C. (deposition date: 2015-10-05, release date: 2015-12-02, Last modification date: 2020-07-29)

• Primary citation: Moraga, I.,Richter, D.,Wilmes, S.,Winkelmann, H.,Jude, K.,Thomas, C.,Suhoski, M.M.,Engleman, E.G.,Piehler, J.,Garcia, K.C.; Instructive roles for cytokine-receptor binding parameters in determining signaling and functional potency.; Sci.Signal., 8:ra114-ra114, 2015; PubMed: 26554818; DOI: 10.1126/scisignal.aab2677

Experimental method

X-RAY DIFFRACTION (3 Å)