7UWK

Structure of the higher-order IL-25-IL-17RB complex

Summary for 7UWK

• Entry DOI: 10.2210/pdb7uwk/pdb
• EMDB information: 26834
• Descriptor: Interleukin-25, Interleukin-17 receptor B (2 entities in total)
• Functional Keywords: receptor complex, il-17e, il-25, il-17rb, cytokine
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 12
• Total formula weight: 330835.79

Authors

Wilson, S.C.,Caveney, N.A.,Jude, K.M.,Garcia, K.C. (deposition date: 2022-05-03, release date: 2022-07-27, Last modification date: 2022-09-28)

• Primary citation: Wilson, S.C.,Caveney, N.A.,Yen, M.,Pollmann, C.,Xiang, X.,Jude, K.M.,Hafer, M.,Tsutsumi, N.,Piehler, J.,Garcia, K.C.; Organizing structural principles of the IL-17 ligand-receptor axis.; Nature, 609:622-629, 2022; PubMed: 35863378; DOI: 10.1038/s41586-022-05116-y

Experimental method

ELECTRON MICROSCOPY (4.4 Å)