7UWM

Structure of the IL-17A-IL-17RA binary complex

Summary for 7UWM

• Entry DOI: 10.2210/pdb7uwm/pdb
• EMDB information: 26836
• Descriptor: Interleukin-17A, Interleukin-17 receptor A, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: receptor complex, il-17a, il-17ra, cytokine
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 142163.01

Authors

Wilson, S.C.,Caveney, N.A.,Jude, K.M.,Garcia, K.C. (deposition date: 2022-05-03, release date: 2022-07-27, Last modification date: 2022-09-28)

• Primary citation: Wilson, S.C.,Caveney, N.A.,Yen, M.,Pollmann, C.,Xiang, X.,Jude, K.M.,Hafer, M.,Tsutsumi, N.,Piehler, J.,Garcia, K.C.; Organizing structural principles of the IL-17 ligand-receptor axis.; Nature, 609:622-629, 2022; PubMed: 35863378; DOI: 10.1038/s41586-022-05116-y

Experimental method

ELECTRON MICROSCOPY (2.5 Å)