7UWM
Structure of the IL-17A-IL-17RA binary complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, D, E | Interleukin-17A | polymer | 169 | 19254.6 | 4 | UniProt (Q16552) Pfam (PF06083) In PDB | Homo sapiens (human) | IL-17,IL-17A,Cytotoxic T-lymphocyte-associated antigen 8,CTLA-8 |
| 2 | C, F | Interleukin-17 receptor A | polymer | 272 | 31585.8 | 2 | UniProt (Q96F46) Pfam (PF16556) Pfam (PF16578) In PDB | Homo sapiens (human) | IL-17 receptor A,IL-17RA,CDw217 |
| 3 | G | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 4 | C, F | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 7 | Chemie (NAG) |
Sequence modifications
A, B, D, E: 25 - 155 (UniProt: Q16552)
| PDB | External Database | Details |
|---|---|---|
| Gly 156 | - | expression tag |
| Ala 157 | - | expression tag |
| Pro 158 | - | expression tag |
| Gly 159 | - | expression tag |
| Ser 160 | - | expression tag |
| Ala 161 | - | expression tag |
| Leu 162 | - | expression tag |
| Glu 163 | - | expression tag |
| Val 164 | - | expression tag |
| Leu 165 | - | expression tag |
| Phe 166 | - | expression tag |
| Gln 167 | - | expression tag |
| Gly 168 | - | expression tag |
| Pro 169 | - | expression tag |
| Gly 170 | - | expression tag |
| Ala 171 | - | expression tag |
| Ala 172 | - | expression tag |
| Gly 173 | - | expression tag |
| Leu 174 | - | expression tag |
| Asn 175 | - | expression tag |
| Asp 176 | - | expression tag |
| Ile 177 | - | expression tag |
| Phe 178 | - | expression tag |
| Glu 179 | - | expression tag |
| Ala 180 | - | expression tag |
| Gln 181 | - | expression tag |
| Lys 182 | - | expression tag |
| Ile 183 | - | expression tag |
| Glu 184 | - | expression tag |
| Trp 185 | - | expression tag |
| His 186 | - | expression tag |
| Glu 187 | - | expression tag |
| His 188 | - | expression tag |
| His 189 | - | expression tag |
| His 190 | - | expression tag |
| His 191 | - | expression tag |
| His 192 | - | expression tag |
| His 193 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 140190.2 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1548.5 | |
| All* | Total formula weight | 142163.0 |
