7UWJ

Structure of the homodimeric IL-25-IL-17RB binary complex

Summary for 7UWJ

Entry DOI	10.2210/pdb7uwj/pdb
EMDB information	26833
Descriptor	Interleukin-25, Interleukin-17 receptor B, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
Functional Keywords	receptor complex, il-17e, il-25, il-17rb, cytokine
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	100699.90
Authors	Wilson, S.C.,Caveney, N.A.,Jude, K.M.,Garcia, K.C. (deposition date: 2022-05-03, release date: 2022-07-27, Last modification date: 2022-09-28)
Primary citation	Wilson, S.C.,Caveney, N.A.,Yen, M.,Pollmann, C.,Xiang, X.,Jude, K.M.,Hafer, M.,Tsutsumi, N.,Piehler, J.,Garcia, K.C. Organizing structural principles of the IL-17 ligand-receptor axis. Nature, 609:622-629, 2022 Cited by PubMed: 35863378 DOI: 10.1038/s41586-022-05116-y PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.2 Å)

Structure validation