7UWN

Structure of the IL-17A-IL-17RA-IL-17RC ternary complex

Summary for 7UWN

• Entry DOI: 10.2210/pdb7uwn/pdb
• EMDB information: 26837
• Descriptor: Interleukin-17A, Interleukin-17 receptor A, Isoform 5 of Interleukin-17 receptor C, ... (5 entities in total)
• Functional Keywords: receptor complex, il-17a, il-17ra, il-17rc, cytokine
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 7
• Total formula weight: 206733.53

Authors

Wilson, S.C.,Caveney, N.A.,Jude, K.M.,Garcia, K.C. (deposition date: 2022-05-03, release date: 2022-07-27, Last modification date: 2022-09-28)

• Primary citation: Wilson, S.C.,Caveney, N.A.,Yen, M.,Pollmann, C.,Xiang, X.,Jude, K.M.,Hafer, M.,Tsutsumi, N.,Piehler, J.,Garcia, K.C.; Organizing structural principles of the IL-17 ligand-receptor axis.; Nature, 609:622-629, 2022; PubMed: 35863378; DOI: 10.1038/s41586-022-05116-y

Experimental method

ELECTRON MICROSCOPY (3.01 Å)