8CTG
Extracellular architecture of an engineered canonical Wnt signaling ternary complex
Summary for 8CTG
| Entry DOI | 10.2210/pdb8ctg/pdb |
| Related | 8FFE |
| EMDB information | 26989 |
| Descriptor | Frizzled-8, Protein Wnt-8, Low-density lipoprotein receptor-related protein 6, ... (4 entities in total) |
| Functional Keywords | signaling complex, beta-catenin, signaling protein |
| Biological source | Mus musculus (house mouse) More |
| Total number of polymer chains | 3 |
| Total formula weight | 125376.99 |
| Authors | Tsutsumi, N.,Jude, K.M.,Garcia, K.C. (deposition date: 2022-05-14, release date: 2023-03-15, Last modification date: 2023-03-22) |
| Primary citation | Tsutsumi, N.,Hwang, S.,Waghray, D.,Hansen, S.,Jude, K.M.,Wang, N.,Miao, Y.,Glassman, C.R.,Caveney, N.A.,Janda, C.Y.,Hannoush, R.N.,Garcia, K.C. Structure of the Wnt-Frizzled-LRP6 initiation complex reveals the basis for coreceptor discrimination. Proc.Natl.Acad.Sci.USA, 120:e2218238120-e2218238120, 2023 Cited by PubMed: 36893265DOI: 10.1073/pnas.2218238120 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.8 Å) |
Structure validation
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