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6WDP

Interleukin 12 receptor subunit beta-1

Summary for 6WDP
Entry DOI10.2210/pdb6wdp/pdb
DescriptorInterleukin-12 receptor subunit beta-1, GLYCEROL, SULFATE ION, ... (4 entities in total)
Functional Keywordscytokine receptor, signaling protein
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total formula weight25069.71
Authors
Spangler, J.B.,Thomas, C.,Jude, K.M.,Garcia, K.C. (deposition date: 2020-04-01, release date: 2021-02-24, Last modification date: 2021-12-01)
Primary citationGlassman, C.R.,Mathiharan, Y.K.,Jude, K.M.,Su, L.,Panova, O.,Lupardus, P.J.,Spangler, J.B.,Ely, L.K.,Thomas, C.,Skiniotis, G.,Garcia, K.C.
Structural basis for IL-12 and IL-23 receptor sharing reveals a gateway for shaping actions on T versus NK cells.
Cell, 184:983-999.e24, 2021
Cited by
PubMed: 33606986
DOI: 10.1016/j.cell.2021.01.018
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.01 Å)
Structure validation

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