4XLW

Complex of Notch1 (EGF11-13) bound to Delta-like 4 (N-EGF2)

Summary for 4XLW

• Entry DOI: 10.2210/pdb4xlw/pdb
• Related: 4XL1
• Descriptor: Neurogenic locus notch homolog protein 1, Delta-like protein, CALCIUM ION, ... (6 entities in total)
• Functional Keywords: glycosylation, egf domains, receptor-ligand complex, protein binding
• Biological source: Rattus norvegicus (Rat); More
• Total number of polymer chains: 8
• Total formula weight: 175246.31

Authors

Luca, V.C.,Jude, K.M.,Garcia, K.C. (deposition date: 2015-01-13, release date: 2015-03-04, Last modification date: 2020-07-29)

• Primary citation: Luca, V.C.,Jude, K.M.,Pierce, N.W.,Nachury, M.V.,Fischer, S.,Garcia, K.C.; Structural biology. Structural basis for Notch1 engagement of Delta-like 4.; Science, 347:847-853, 2015; PubMed: 25700513; DOI: 10.1126/science.1261093

Experimental method

X-RAY DIFFRACTION (3.39 Å)