4XLW
Complex of Notch1 (EGF11-13) bound to Delta-like 4 (N-EGF2)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C, E, G | Neurogenic locus notch homolog protein 1 | polymer | 124 | 13524.2 | 4 | UniProt (Q07008) Pfam (PF07645) Pfam (PF12661) Pfam (PF00008) In PDB | Rattus norvegicus (Rat) | Notch 1 |
2 | B, D, F, H | Delta-like protein | polymer | 261 | 29150.7 | 4 | UniProt (D3ZHH1) Pfam (PF07657) Pfam (PF01414) Pfam (PF21795) In PDB | Rattus norvegicus (Rat) | |
3 | G, A, C, E | CALCIUM ION | non-polymer | 40.1 | 10 | Chemie (CA) | |||
4 | E, G, A, C | beta-D-glucopyranose | non-polymer | 180.2 | 12 | Chemie (BGC) | |||
5 | E, G, A, C | alpha-L-fucopyranose | non-polymer | 164.2 | 4 | Chemie (FUC) | |||
6 | F, H, B, D | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) |
Sequence modifications
A, C, E, G: 412 - 526 (UniProt: Q07008)
B, D, F, H: 27 - 283 (UniProt: D3ZHH1)
PDB | External Database | Details |
---|---|---|
Ser 527 | - | expression tag |
Gly 528 | - | expression tag |
Arg 529 | - | expression tag |
Leu 530 | - | expression tag |
Glu 531 | - | expression tag |
Val 532 | - | expression tag |
Leu 533 | - | expression tag |
Phe 534 | - | expression tag |
Gln 535 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Ser 26 | - | expression tag |
Ser 28 | Gly 28 | engineered mutation |
Leu 107 | Phe 107 | engineered mutation |
Pro 206 | Leu 206 | engineered mutation |
Lys 257 | Asn 257 | engineered mutation |
Ala 284 | - | expression tag |
Ala 285 | - | expression tag |
Ala 286 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 170699.8 | |
Non-Polymers* | Number of molecules | 32 |
Total formula weight | 4546.5 | |
All* | Total formula weight | 175246.3 |