4XL1

Complex of Notch1 (EGF11-13) bound to Delta-like 4 (N-EGF1)

Summary for 4XL1

Entry DOI	10.2210/pdb4xl1/pdb
Descriptor	Neurogenic locus notch homolog protein 1, Delta-like protein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
Functional Keywords	glycosylation, egf domains, receptor-ligand complex, protein binding
Biological source	Rattus norvegicus (Rat) More
Total number of polymer chains	4
Total formula weight	80361.57
Authors	Luca, V.C.,Jude, K.M.,Garcia, K.C. (deposition date: 2015-01-13, release date: 2015-03-04, Last modification date: 2020-07-29)
Primary citation	Luca, V.C.,Jude, K.M.,Pierce, N.W.,Nachury, M.V.,Fischer, S.,Garcia, K.C. Structural biology. Structural basis for Notch1 engagement of Delta-like 4. Science, 347:847-853, 2015 Cited by PubMed: 25700513 DOI: 10.1126/science.1261093 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation