8SK5
| Crystal structure of the SARS-CoV-2 neutralizing VHH 7A9 bound to the spike receptor binding domain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, anti-SARS-CoV-2 receptor binding domain VHH | 著者 | Noland, C.L, Pande, K, Zhang, L, Zhou, H, Galli, J, Eddins, M, Gomez-Llorente, Y. | 登録日 | 2023-04-18 | 公開日 | 2023-08-16 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2.011 Å) | 主引用文献 | Discovery and multimerization of cross-reactive single-domain antibodies against SARS-like viruses to enhance potency and address emerging SARS-CoV-2 variants. Sci Rep, 13, 2023
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3KG0
| Crystal structure of SnoaB, a cofactor-independent oxygenase from Streptomyces nogalater, determined to 1.7 resolution | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, SnoaB | 著者 | Koskiniemi, H, Grocholski, T, Lindqvist, Y, Mantsala, P, Niemi, J, Schneider, G. | 登録日 | 2009-10-28 | 公開日 | 2010-01-26 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structure of the cofactor-independent monooxygenase SnoaB from Streptomyces nogalater: implications for the reaction mechanism Biochemistry, 49, 2010
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7S0G
| Isoproterenol bound beta1 adrenergic receptor in complex with heterotrimeric Gi/s chimera protein | 分子名称: | Beta1-Adrenergic Receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Paknejad, N, Alegre, K.O, Su, M, Lou, J.S, Huang, J, Jordan, K.D, Eng, E.T, Meyerson, J.R, Hite, R.K, Huang, X.Y. | 登録日 | 2021-08-30 | 公開日 | 2021-11-17 | 最終更新日 | 2021-12-01 | 実験手法 | ELECTRON MICROSCOPY (3.86 Å) | 主引用文献 | Structural basis and mechanism of activation of two different families of G proteins by the same GPCR. Nat.Struct.Mol.Biol., 28, 2021
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3TKG
| crystal structure of HIV model protease precursor/saquinavir complex | 分子名称: | (2S)-N-[(2S,3R)-4-[(2S,3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1 -phenyl-butan-2-yl]-2-(quinolin-2-ylcarbonylamino)butanediamide, CHLORIDE ION, GLYCEROL, ... | 著者 | Agniswamy, J, Sayer, J, Weber, I, Louis, J. | 登録日 | 2011-08-26 | 公開日 | 2012-04-25 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | 主引用文献 | Terminal interface conformations modulate dimer stability prior to amino terminal autoprocessing of HIV-1 protease. Biochemistry, 51, 2012
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5KQR
| Structure of NS5 methyltransferase from Zika virus bound to S-adenosylmethionine | 分子名称: | CHLORIDE ION, Methyltransferase, PHOSPHATE ION, ... | 著者 | Jain, R, Coloma, J, Rajashankar, K.R, Aggarwal, A.K. | 登録日 | 2016-07-06 | 公開日 | 2016-09-14 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.331 Å) | 主引用文献 | Structures of NS5 Methyltransferase from Zika Virus. Cell Rep, 16, 2016
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7S3D
| Structure of photosystem I with bound ferredoxin from Synechococcus sp. PCC 7335 acclimated to far-red light | 分子名称: | 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, 2Fe-2S ferredoxin-type domain-containing protein, ... | 著者 | Gisriel, C.J, Flesher, D.A, Shen, G, Wang, J, Ho, M, Brudvig, G.W, Bryant, D.A. | 登録日 | 2021-09-05 | 公開日 | 2021-11-24 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.91 Å) | 主引用文献 | Structure of a photosystem I-ferredoxin complex from a marine cyanobacterium provides insights into far-red light photoacclimation. J.Biol.Chem., 298, 2021
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1XDF
| Crystal structure of pathogenesis-related protein LlPR-10.2A from yellow lupine | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, PR10.2A, SODIUM ION | 著者 | Pasternak, O, Biesiadka, J, Dolot, R, Handschuh, L, Bujacz, G, Sikorski, M.M, Jaskolski, M. | 登録日 | 2004-09-06 | 公開日 | 2005-02-15 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure of a yellow lupin pathogenesis-related PR-10 protein belonging to a novel subclass. Acta Crystallogr.,Sect.D, 61, 2005
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5WTB
| Complex Structure of Staphylococcus aureus SdrE with human complement factor H | 分子名称: | Peptide from Complement factor H, Serine-aspartate repeat-containing protein E | 著者 | Wu, M, Zhang, Y, Hang, T, Wang, C, Yang, Y, Zang, J, Zhang, M, Zhang, X. | 登録日 | 2016-12-10 | 公開日 | 2017-07-19 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Staphylococcus aureus SdrE captures complement factor H's C-terminus via a novel 'close, dock, lock and latch' mechanism for complement evasion Biochem. J., 474, 2017
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2PJL
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5KPP
| Structure of human PARP1 catalytic domain bound to a quinazoline-2,4(1H,3H)-dione inhibitor | 分子名称: | 1-[[4-fluoranyl-3-[(3R)-3-methyl-4-[2,2,2-tris(fluoranyl)ethyl]piperazin-1-yl]carbonyl-phenyl]methyl]quinazoline-2,4-dione, Poly [ADP-ribose] polymerase 1 | 著者 | Cao, R, Wang, Y.L, Zhou, J, Huang, N, Xu, B.L. | 登録日 | 2016-07-05 | 公開日 | 2016-11-30 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | Structure of human PARP1 catalytic domain bound to a quinazoline-2,4(1H,3H)-dione inhibitor To Be Published
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7KBH
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2PMN
| Crystal structure of PfPK7 in complex with an ATP-site inhibitor | 分子名称: | 4-(6-{[(1S)-1-(HYDROXYMETHYL)-2-METHYLPROPYL]AMINO}IMIDAZO[1,2-B]PYRIDAZIN-3-YL)BENZONITRILE, Ser/Thr protein kinase, putative | 著者 | Merckx, A, Echalier, A, Noble, M, Endicott, J. | 登録日 | 2007-04-23 | 公開日 | 2008-01-22 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structures of P. falciparum protein kinase 7 identify an activation motif and leads for inhibitor design. Structure, 16, 2008
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8URK
| Crystal structure of DNA N6-Adenine Methyltransferase M.BceJIV from Burkholderia cenocepacia in complex with duplex DNA substrates | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DNA1, DNA2, ... | 著者 | Kottur, J, Quintana-Feliciano, R, Aggarwal, A.K. | 登録日 | 2023-10-26 | 公開日 | 2024-09-11 | 最終更新日 | 2024-09-25 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | Burkholderia cenocepacia epigenetic regulator M.BceJIV simultaneously engages two DNA recognition sequences for methylation. Nat Commun, 15, 2024
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5KR6
| Directed Evolution of Transaminases By Ancestral Reconstruction. Using Old Proteins for New Chemistries | 分子名称: | 4-aminobutyrate transaminase, PYRIDOXAL-5'-PHOSPHATE | 著者 | Wilding, M, Newman, J, Peat, T.S, Scott, C. | 登録日 | 2016-07-07 | 公開日 | 2017-07-12 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Reverse engineering: transaminase biocatalyst development using ancestral sequence reconstruction Green Chemistry, 19, 2017
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3R4U
| Cell entry of botulinum neurotoxin type C is dependent upon interaction with two ganglioside molecules | 分子名称: | Botulinum neurotoxin type C1 | 著者 | Strotmeier, J, Gu, S, Jutzi, S, Mahrhold, S, Zhou, J, Pich, A, Bigalke, H, Rummel, A, Jin, R, Binz, T. | 登録日 | 2011-03-17 | 公開日 | 2011-06-08 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The biological activity of botulinum neurotoxin type C is dependent upon novel types of ganglioside binding sites. Mol.Microbiol., 81, 2011
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7S3G
| Structure of cofactor pyridoxal 5-phosphate bound human ornithine decarboxylase in complex with citrate at the catalytic center | 分子名称: | CITRIC ACID, Ornithine decarboxylase, PYRIDOXAL-5'-PHOSPHATE | 著者 | Zhou, X.E, Suino-Powell, K, Schultz, C.R, Aleiwi, B, Brunzelle, J.S, Lamp, J, Vega, I.E, Ellsworth, E, Bachmann, A.S, Melcher, K. | 登録日 | 2021-09-06 | 公開日 | 2021-12-15 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | Structural basis of binding and inhibition of ornithine decarboxylase by 1-amino-oxy-3-aminopropane. Biochem.J., 478, 2021
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5WZJ
| Structure of APUM23-GGAUUUGACGG | 分子名称: | Pumilio homolog 23, RNA (5'-R(*GP*GP*AP*UP*UP*UP*GP*AP*CP*GP*G)-3') | 著者 | Bao, H, Wang, N, Wang, C, Jiang, Y, Wu, J, Shi, Y. | 登録日 | 2017-01-18 | 公開日 | 2017-09-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.101 Å) | 主引用文献 | Structural basis for the specific recognition of 18S rRNA by APUM23. Nucleic Acids Res., 45, 2017
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8D1U
| E. coli beta-ketoacyl-[acyl carrier protein] synthase III (FabH) with an acetylated cysteine and in complex with oxa(dethia)-Coenzyme A | 分子名称: | 3-oxoacyl-[acyl-carrier-protein] synthase 3, CHLORIDE ION, oxa(dethia)-CoA | 著者 | Benjamin, A.B, Stunkard, L.M, Ling, J, Nice, J.N, Lohman, J.R. | 登録日 | 2022-05-27 | 公開日 | 2022-06-15 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (1.302 Å) | 主引用文献 | Structures of chloramphenicol acetyltransferase III and Escherichia coli beta-ketoacylsynthase III co-crystallized with partially hydrolysed acetyl-oxa(dethia)CoA. Acta Crystallogr.,Sect.F, 79, 2023
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7JNA
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7W7Q
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8UCP
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8UCN
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7SF6
| Crystal Structure of Siderophore Binding Protein FatB from Desulfitobacterium hafniense | 分子名称: | 1,2-ETHANEDIOL, 2-(2,3-DIHYDROXY-BENZOYLAMINO)-3-HYDROXY-PROPIONIC ACID, CHLORIDE ION, ... | 著者 | Kim, Y, Patel, H.P, Nordquist, K.A, Schaab, K.M, Sha, J, Babnigg, G, Bond, A.H, Joachimiak, A, Midwest Center for Structural Genomics, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2021-10-03 | 公開日 | 2021-12-15 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | 主引用文献 | Crystal Structure of Siderophore Binding Protein FatB from Desulfitobacterium hafniense To Be Published
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8UCK
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5KLQ
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