6KDN
| HIV-1 reverse transcriptase with Q151M/Y115F/F116Y:DNA:dGTP ternary complex | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA/RNA (38-MER), GLYCEROL, ... | Authors: | Yasutake, Y, Hattori, S.I, Tamura, N, Maeda, K. | Deposit date: | 2019-07-02 | Release date: | 2020-03-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.303 Å) | Cite: | Structural features in common of HBV and HIV-1 resistance against chirally-distinct nucleoside analogues entecavir and lamivudine. Sci Rep, 10, 2020
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1XLP
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6KDJ
| HIV-1 reverse transcriptase with Q151M/Y115F/F116Y:DNA:lamivudine 5'-triphosphate ternary complex | Descriptor: | DNA/RNA (38-MER), GLYCEROL, HIV-1 RT p51 subunit, ... | Authors: | Yasutake, Y, Hattori, S.I, Tamura, N, Maeda, K. | Deposit date: | 2019-07-02 | Release date: | 2020-03-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Structural features in common of HBV and HIV-1 resistance against chirally-distinct nucleoside analogues entecavir and lamivudine. Sci Rep, 10, 2020
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1XPL
| Crystal Structure of Staphylococcus aureus HMG-COA Synthase with Acetoacetyl-COA and Acetylated Cysteine | Descriptor: | 3-hydroxy-3-methylglutaryl CoA synthase, ACETOACETYL-COENZYME A, SULFATE ION | Authors: | Theisen, M.J, Misra, I, Saadat, D, Campobasso, N, Miziorko, H.M, Harrison, D.H.T. | Deposit date: | 2004-10-08 | Release date: | 2004-11-02 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | 3-hydroxy-3-methylglutaryl-CoA synthase intermediate complex observed in "real-time" Proc.Natl.Acad.Sci.USA, 47, 2004
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1XRG
| Conserved hypothetical protein from Clostridium thermocellum Cth-2968 | Descriptor: | Putative translation initiation inhibitor, yjgF family, UNKNOWN ATOM OR ION | Authors: | Zhao, M, Chang, J, Habel, J, Kataeva, I, Xu, H, Chen, L, Lee, D, Nguyen, J, Chang, S.-H, Horanyi, P, Florence, Q, Zhou, W, Tempel, W, Lin, D, Zhang, H, Arendall III, W.B, Ljundahl, L, Liu, Z.-J, Rose, J, Richardson, J.S, Richardson, D.C, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG) | Deposit date: | 2004-10-14 | Release date: | 2004-12-14 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Conserved hypothetical protein from Clostridium thermocellum Cth-2968 To be published
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7K9Z
| Crystal structure of SARS-CoV-2 receptor binding domain in complex with the Fab fragments of neutralizing antibodies 298 and 52 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 298 Fab Heavy Chain, 298 Fab Light Chain, ... | Authors: | Newton, J.C, Kucharska, I, Rujas, E, Cui, H, Julien, J.P. | Deposit date: | 2020-09-29 | Release date: | 2020-10-28 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Multivalency transforms SARS-CoV-2 antibodies into ultrapotent neutralizers. Nat Commun, 12, 2021
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6ME1
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8V06
| Crystal structure of mouse PLD3 co-crystallized with 5'Pi-ssDNA for 9 days | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5'-3' exonuclease PLD3, ... | Authors: | Yuan, M, Wilson, I.A. | Deposit date: | 2023-11-17 | Release date: | 2024-03-13 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.73 Å) | Cite: | Structural and mechanistic insights into disease-associated endolysosomal exonucleases PLD3 and PLD4. Structure, 32, 2024
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6MEH
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6M58
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1UDY
| Medium-Chain Acyl-CoA Dehydrogenase with 3-Thiaoctanoyl-CoA | Descriptor: | 3-THIAOCTANOYL-COENZYME A, Acyl-CoA dehydrogenase, medium-chain specific, ... | Authors: | Satoh, A, Nakajima, Y, Miyahara, I, Hirotsu, K, Tanaka, T, Nishina, Y, Shiga, K, Tamaoki, H, Setoyama, C, Miura, R. | Deposit date: | 2003-05-07 | Release date: | 2003-12-09 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of the transition state analog of medium-chain acyl-CoA dehydrogenase. Crystallographic and molecular orbital studies on the charge-transfer complex of medium-chain acyl-CoA dehydrogenase with 3-thiaoctanoyl-CoA J.BIOCHEM.(TOKYO), 134, 2003
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3ERX
| High-resolution structure of Paracoccus pantotrophus pseudoazurin | Descriptor: | COPPER (II) ION, Pseudoazurin, SULFATE ION | Authors: | Najmudin, S, Pauleta, S.R, Moura, I, Romao, M.J. | Deposit date: | 2008-10-03 | Release date: | 2009-10-13 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | The 1.4 A resolution structure of Paracoccus pantotrophus pseudoazurin. Acta Crystallogr.,Sect.F, 66, 2010
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2H8P
| Structure of a K channel with an amide to ester substitution in the selectivity filter | Descriptor: | (2S)-2-(BUTYRYLOXY)-3-HYDROXYPROPYL NONANOATE, FAB heavy chain, FAB light chain, ... | Authors: | Valiyaveetil, F.I, MacKinnon, R, Muir, T.W. | Deposit date: | 2006-06-07 | Release date: | 2006-09-12 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural and Functional Consequences of an Amide-to-Ester Substitution in the Selectivity Filter of a Potassium Channel. J.Am.Chem.Soc., 128, 2006
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4MVA
| 1.43 Angstrom Resolution Crystal Structure of Triosephosphate Isomerase (tpiA) from Escherichia coli in Complex with Acetyl Phosphate. | Descriptor: | 1,2-ETHANEDIOL, ACETYLPHOSPHATE, CHLORIDE ION, ... | Authors: | Minasov, G, Kuhn, M.L, Dubrovska, I, Winsor, J, Shuvalova, L, Grimshaw, S, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2013-09-23 | Release date: | 2014-04-16 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.43 Å) | Cite: | Structural, kinetic and proteomic characterization of acetyl phosphate-dependent bacterial protein acetylation. Plos One, 9, 2014
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3V47
| Crystal structure of the N-terminal fragment of zebrafish TLR5 in complex with Salmonella flagellin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Flagellin, ... | Authors: | Yoon, S.I, Hong, H, Wilson, I.A. | Deposit date: | 2011-12-14 | Release date: | 2012-02-29 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | Structural basis of TLR5-flagellin recognition and signaling. Science, 335, 2012
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1U2G
| transhydrogenase (dI.ADPr)2(dIII.NADPH)1 asymmetric complex | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, GLYCEROL, NAD(P) transhydrogenase subunit alpha part 1, ... | Authors: | Mather, O.C, Singh, A, van Boxel, G.I, White, S.A, Jackson, J.B. | Deposit date: | 2004-07-19 | Release date: | 2005-01-25 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Active-site conformational changes associated with hydride transfer in proton-translocating transhydrogenase. Biochemistry, 43, 2004
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7LQY
| Structure of squirrel TRPV1 in apo state | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoinositol, CHLORIDE ION, ... | Authors: | Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I. | Deposit date: | 2021-02-15 | Release date: | 2021-04-21 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.19 Å) | Cite: | Extracellular cap domain is an essential component of the TRPV1 gating mechanism. Nat Commun, 12, 2021
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1U8V
| Crystal Structure of 4-Hydroxybutyryl-CoA Dehydratase from Clostridium aminobutyricum: Radical catalysis involving a [4Fe-4S] cluster and flavin | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Gamma-aminobutyrate metabolism dehydratase/isomerase, IRON/SULFUR CLUSTER | Authors: | Martins, B.M, Dobbek, H, Cinkaya, I, Buckel, W, Messerschmidt, A. | Deposit date: | 2004-08-07 | Release date: | 2004-12-21 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of 4-hydroxybutyryl-CoA dehydratase: radical catalysis involving a [4Fe-4S] cluster and flavin. Proc.Natl.Acad.Sci.USA, 101, 2004
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7LR0
| Structure of squirrel TRPV1 in complex with capsaicin | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, (6E)-N-(4-hydroxy-3-methoxybenzyl)-8-methylnon-6-enamide, Osm-9-like TRP channel 1, ... | Authors: | Neuberger, A, Nadezhdin, K.D, Sobolevsky, A.I. | Deposit date: | 2021-02-15 | Release date: | 2021-04-21 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.81 Å) | Cite: | Extracellular cap domain is an essential component of the TRPV1 gating mechanism. Nat Commun, 12, 2021
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8W0V
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7LQZ
| Structure of squirrel TRPV1 in complex with RTX | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Osm-9-like TRP channel 1, SODIUM ION, ... | Authors: | Neuberger, A, Nadezhdin, K.D, Sobolevsky, A.I. | Deposit date: | 2021-02-15 | Release date: | 2021-04-21 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.41 Å) | Cite: | Extracellular cap domain is an essential component of the TRPV1 gating mechanism. Nat Commun, 12, 2021
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6LX8
| X-ray structure of human PPARalpha ligand binding domain-oleic acid co-crystals obtained by delipidation and cross-seeding | Descriptor: | GLYCEROL, OLEIC ACID, Peroxisome proliferator-activated receptor alpha | Authors: | Kamata, S, Saito, K, Honda, A, Ishikawa, R, Oyama, T, Ishii, I. | Deposit date: | 2020-02-10 | Release date: | 2020-11-11 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | PPAR alpha Ligand-Binding Domain Structures with Endogenous Fatty Acids and Fibrates. Iscience, 23, 2020
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6M4F
| Crystal structure of the E496A mutant of HsBglA | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-galactosidase-like enzyme, ... | Authors: | Uehara, R, Iwamoto, R, Aoki, S, Yoshizawa, T, Takano, K, Matsumura, H, Tanaka, S.-i. | Deposit date: | 2020-03-06 | Release date: | 2020-09-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of a GH1 beta-glucosidase from Hamamotoa singularis. Protein Sci., 29, 2020
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3R5Z
| Structure of a Deazaflavin-dependent reductase from Nocardia farcinica, with co-factor F420 | Descriptor: | COENZYME F420, Putative uncharacterized protein, SULFATE ION | Authors: | Cellitti, S.E, Shaffer, J, Jones, D.H, Mukherjee, T, Gurumurthy, M, Bursulaya, B, Boshoff, H.I.M, Choi, I, Nayya, A, Lee, Y.S, Cherian, J, Niyomrattanakit, P, Dick, T, Manjunatha, U.H, Barry, C.E, Spraggon, G, Geierstanger, B.H. | Deposit date: | 2011-03-20 | Release date: | 2012-01-18 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.503 Å) | Cite: | Structure of Ddn, the deazaflavin-dependent nitroreductase from Mycobacterium tuberculosis involved in bioreductive activation of PA-824. Structure, 20, 2012
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1XPK
| CRYSTAL STRUCTURE OF STAPHYLOCOCCUS AUREUS HMG-COA SYNTHASE WITH HMG-CoA AND WITH ACETOACETYL-COA AND ACETYLATED CYSTEINE | Descriptor: | 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A, 3-hydroxy-3-methylglutaryl CoA synthase, ACETOACETYL-COENZYME A, ... | Authors: | Theisen, M.J, Misra, I, Saadat, D, Campobasso, N, Miziorko, H.M, Harrison, D.H.T. | Deposit date: | 2004-10-08 | Release date: | 2004-11-02 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | 3-hydroxy-3-methylglutaryl-CoA synthase intermediate complex observed in "real-time" Proc.Natl.Acad.Sci.USA, 47, 2004
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