6KDJ

HIV-1 reverse transcriptase with Q151M/Y115F/F116Y:DNA:lamivudine 5'-triphosphate ternary complex

Summary for 6KDJ

Entry DOI	10.2210/pdb6kdj/pdb
Related PRD ID	PRD_900003
Descriptor	HIV-1 reverse transcriptase p66 subunit, HIV-1 RT p51 subunit, DNA/RNA (38-MER), ... (8 entities in total)
Functional Keywords	lamivudine 5'-triphosphate, hiv-1, hbv, reverse transcriptase, drug resistance, drug sensitivity, transferase-dna complex, replication, transferase/dna
Biological source	Human immunodeficiency virus 1 More
Total number of polymer chains	6
Total formula weight	257016.59
Authors	Yasutake, Y.,Hattori, S.I.,Tamura, N.,Maeda, K. (deposition date: 2019-07-02, release date: 2020-03-04, Last modification date: 2023-11-22)
Primary citation	Yasutake, Y.,Hattori, S.I.,Tamura, N.,Matsuda, K.,Kohgo, S.,Maeda, K.,Mitsuya, H. Structural features in common of HBV and HIV-1 resistance against chirally-distinct nucleoside analogues entecavir and lamivudine. Sci Rep, 10:3021-3021, 2020 Cited by PubMed: 32080249 DOI: 10.1038/s41598-020-59775-w PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.51 Å)

Structure validation