6KDJ
HIV-1 reverse transcriptase with Q151M/Y115F/F116Y:DNA:lamivudine 5'-triphosphate ternary complex
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003676 | molecular_function | nucleic acid binding |
A | 0003964 | molecular_function | RNA-directed DNA polymerase activity |
A | 0004523 | molecular_function | RNA-DNA hybrid ribonuclease activity |
A | 0006278 | biological_process | RNA-templated DNA biosynthetic process |
B | 0003964 | molecular_function | RNA-directed DNA polymerase activity |
B | 0006278 | biological_process | RNA-templated DNA biosynthetic process |
C | 0003676 | molecular_function | nucleic acid binding |
C | 0003964 | molecular_function | RNA-directed DNA polymerase activity |
C | 0004523 | molecular_function | RNA-DNA hybrid ribonuclease activity |
C | 0006278 | biological_process | RNA-templated DNA biosynthetic process |
D | 0003964 | molecular_function | RNA-directed DNA polymerase activity |
D | 0006278 | biological_process | RNA-templated DNA biosynthetic process |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 14 |
Details | BINDING: BINDING => ECO:0000250 |
Chain | Residue | Details |
A | ASP110 | |
C | ASP186 | |
C | ASP443 | |
C | GLU478 | |
C | ASP498 | |
C | ASP549 | |
A | ASP185 | |
A | ASP186 | |
A | ASP443 | |
A | GLU478 | |
A | ASP498 | |
A | ASP549 | |
C | ASP110 | |
C | ASP185 |
site_id | SWS_FT_FI2 |
Number of Residues | 4 |
Details | SITE: Essential for RT p66/p51 heterodimerization => ECO:0000250 |
Chain | Residue | Details |
A | TRP401 | |
A | TRP414 | |
C | TRP401 | |
C | TRP414 |
site_id | SWS_FT_FI3 |
Number of Residues | 2 |
Details | SITE: Cleavage; by viral protease; partial => ECO:0000250 |
Chain | Residue | Details |
A | PHE440 | |
C | PHE440 |