2H8P

Structure of a K channel with an amide to ester substitution in the selectivity filter

Summary for 2H8P

Entry DOI	10.2210/pdb2h8p/pdb
Descriptor	FAB heavy chain, FAB light chain, KcsA Channel, ... (6 entities in total)
Functional Keywords	channel, semi-synthetic, ester, membrane protein
Biological source	Mus musculus (house mouse) More
Cellular location	Cell membrane; Multi-pass membrane protein: 2H8P
Total number of polymer chains	3
Total formula weight	58166.52
Authors	Valiyaveetil, F.I.,MacKinnon, R.,Muir, T.W. (deposition date: 2006-06-07, release date: 2006-09-12, Last modification date: 2024-03-27)
Primary citation	Valiyaveetil, F.I.,Sekedat, M.,Mackinnon, R.,Muir, T.W. Structural and Functional Consequences of an Amide-to-Ester Substitution in the Selectivity Filter of a Potassium Channel. J.Am.Chem.Soc., 128:11591-11599, 2006 Cited by PubMed: 16939283 DOI: 10.1021/ja0631955 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation