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1XPK

CRYSTAL STRUCTURE OF STAPHYLOCOCCUS AUREUS HMG-COA SYNTHASE WITH HMG-CoA AND WITH ACETOACETYL-COA AND ACETYLATED CYSTEINE

Summary for 1XPK
Entry DOI10.2210/pdb1xpk/pdb
Related1XPL 1XPM
Descriptor3-hydroxy-3-methylglutaryl CoA synthase, SULFATE ION, 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A, ... (6 entities in total)
Functional Keywordshmg-coa synthase, hmgs, coenzyme a, thiolase fold, condensing enzyme, cholesterol biosynthesis, transferase
Biological sourceStaphylococcus aureus subsp. aureus
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Total number of polymer chains4
Total formula weight179178.61
Authors
Theisen, M.J.,Misra, I.,Saadat, D.,Campobasso, N.,Miziorko, H.M.,Harrison, D.H.T. (deposition date: 2004-10-08, release date: 2004-11-02, Last modification date: 2023-09-20)
Primary citationTheisen, M.J.,Misra, I.,Saadat, D.,Campobasso, N.,Miziorko, H.M.,Harrison, D.H.T.
3-hydroxy-3-methylglutaryl-CoA synthase intermediate complex observed in "real-time"
Proc.Natl.Acad.Sci.USA, 47:16442-16447, 2004
Cited by
PubMed: 15498869
DOI: 10.1073/pnas.0405809101
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

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