6M58

Crystal structure of a complex between human serum albumin and the antibody Fab SL335

Summary for 6M58

Entry DOI	10.2210/pdb6m58/pdb
Descriptor	Serum albumin, Heavy chain of the SL335 antibody fab, Light chain of the SL335 antibody Fab, ... (4 entities in total)
Functional Keywords	serum albumin, anti-albumin, antibody fab, immune system
Biological source	Homo sapiens (Human) More
Total number of polymer chains	6
Total formula weight	228362.70
Authors	Cho, S.Y.,Yoon, S.I. (deposition date: 2020-03-10, release date: 2020-04-29, Last modification date: 2023-11-29)
Primary citation	Cho, S.Y.,Han, J.,Cha, S.H.,Yoon, S.I. Structural basis of serum albumin recognition by SL335, an antibody Fab extending the serum half-life of protein therapeutics. Biochem.Biophys.Res.Commun., 526:941-946, 2020 Cited by PubMed: 32284170 DOI: 10.1016/j.bbrc.2020.03.133 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.95 Å)

Structure validation