6KDN

HIV-1 reverse transcriptase with Q151M/Y115F/F116Y:DNA:dGTP ternary complex

Summary for 6KDN

• Entry DOI: 10.2210/pdb6kdn/pdb
• Descriptor: HIV-1 reverse transcriptase p66 subunit, HIV-1 RT p51 subunit, DNA/RNA (38-MER), ... (7 entities in total)
• Functional Keywords: entecavir 5'-triphosphate, hiv-1, hbv, reverse transcriptase, drug resistance, drug sensitivity, transferase-dna complex, replication, transferase/dna
• Biological source: Human immunodeficiency virus 1; More
• Total number of polymer chains: 6
• Total formula weight: 256762.31

Authors

Yasutake, Y.,Hattori, S.I.,Tamura, N.,Maeda, K. (deposition date: 2019-07-02, release date: 2020-03-04, Last modification date: 2023-11-22)

• Primary citation: Yasutake, Y.,Hattori, S.I.,Tamura, N.,Matsuda, K.,Kohgo, S.,Maeda, K.,Mitsuya, H.; Structural features in common of HBV and HIV-1 resistance against chirally-distinct nucleoside analogues entecavir and lamivudine.; Sci Rep, 10:3021-3021, 2020; PubMed: 32080249; DOI: 10.1038/s41598-020-59775-w

Experimental method

X-RAY DIFFRACTION (2.303 Å)