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PDB: 208 件
5AYS
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BU of 5ays by Molmil
Crystal structure of SAUGI/HSV UDG complex
分子名称: Uncharacterized protein, Uracil-DNA glycosylase
著者Wang, H.C, Ko, T.P, Huang, M.F, Wang, A.H.J.
登録日2015-09-02
公開日2016-06-08
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Using structural-based protein engineering to modulate the differential inhibition effects of SAUGI on human and HSV uracil DNA glycosylase.
Nucleic Acids Res., 44, 2016
5EW6
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BU of 5ew6 by Molmil
Structure of ligand binding region of uPARAP at pH 7.4 without calcium
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C-type mannose receptor 2, ...
著者Yuan, C, Huang, M.
登録日2015-11-20
公開日2016-08-10
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Crystal structures of the ligand-binding region of uPARAP: effect of calcium ion binding
Biochem.J., 473, 2016
4DW2
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BU of 4dw2 by Molmil
The crystal structure of uPA in complex with the Fab fragment of mAb-112
分子名称: Fab fragment of pro-uPA antibody mAb-112, SULFATE ION, Urokinase-type plasminogen activator
著者Jiang, L, Botkjaer, K.A, Andersen, L.M, Yuan, C, Andreasen, P.A, Huang, M.
登録日2012-02-24
公開日2013-01-16
実験手法X-RAY DIFFRACTION (2.97 Å)
主引用文献Rezymogenation of active urokinase induced by an inhibitory antibody.
Biochem.J., 449, 2013
5E4K
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BU of 5e4k by Molmil
Structure of ligand binding region of uPARAP at pH 7.4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, C-type mannose receptor 2, ...
著者Yuan, C, Huang, M.
登録日2015-10-06
公開日2016-08-10
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Crystal structures of the ligand-binding region of uPARAP: effect of calcium ion binding
Biochem.J., 473, 2016
4DVA
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BU of 4dva by Molmil
The crystal structure of human urokinase-type plasminogen activator catalytic domain
分子名称: HEXAETHYLENE GLYCOL, SULFATE ION, Urokinase-type plasminogen activator
著者Jiang, L, Botkjaer, K.A, Andersen, L.M, Yuan, C, Andreasen, P.A, Huang, M.
登録日2012-02-23
公開日2013-01-16
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Rezymogenation of active urokinase induced by an inhibitory antibody
Biochem.J., 449, 2013
4ZKR
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BU of 4zkr by Molmil
The crystal structure of upain-1-W3A in complex with uPA at pH9.0
分子名称: HEXAETHYLENE GLYCOL, SULFATE ION, Urokinase-type plasminogen activator, ...
著者Jiang, L, Andreasen, P.A, Huang, M.
登録日2015-04-30
公開日2016-05-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.36 Å)
主引用文献The crystal structure of mupain-1-IG in complex with murinised human uPA at pH7.4
To Be Published
4ZKS
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BU of 4zks by Molmil
The crystal structure of upain-1-W3A in complex with inactive uPA (uPA-S195A) at pH7.4
分子名称: Urokinase-type plasminogen activator, upain-1-W3A
著者Jiang, L, Andreasen, P.A, Huang, M.
登録日2015-04-30
公開日2016-05-18
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The crystal structure of mupain-1-IG in complex with murinised human uPA at pH7.4
To Be Published
4ZKN
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BU of 4zkn by Molmil
The crystal structure of upain-1-W3A in complex with uPA at pH5.5
分子名称: SULFATE ION, TETRAETHYLENE GLYCOL, Urokinase-type plasminogen activator, ...
著者Jiang, L, Andreasen, P.A, Huang, M.
登録日2015-04-30
公開日2016-05-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.36 Å)
主引用文献The crystal structure of mupain-1-IG in complex with murinised human uPA at pH7.4
To Be Published
6A8G
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BU of 6a8g by Molmil
The crystal structure of muPAin-1-IG in complex with muPA-SPD at pH8.5
分子名称: PHOSPHATE ION, Urokinase-type plasminogen activator chain B, muPAin-1-IG
著者Wang, D, Yang, Y.S, Jiang, L.G, Huang, M.D, Li, J.Y, Andreasen, P.A, Xu, P, Chen, Z.
登録日2018-07-08
公開日2019-02-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Suppression of Tumor Growth and Metastases by Targeted Intervention in Urokinase Activity with Cyclic Peptides.
J.Med.Chem., 62, 2019
6AG7
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BU of 6ag7 by Molmil
The crystal structure of uPA in complex with HMA-55F
分子名称: 3,5-diamino-N-carbamimidoyl-6-(1-methyl-1H-pyrazol-4-yl)pyrazine-2-carboxamide, Urokinase-type plasminogen activator
著者Buckley, B, Jiang, L.G, Majed, H, Huang, M.D, Kelso, M, Ranson, M.
登録日2018-08-09
公開日2019-08-14
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献uPA-HMA
To Be Published
6A8N
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BU of 6a8n by Molmil
The crystal structure of muPAin-1-IG-2 in complex with muPA-SPD at pH8.5
分子名称: CYS-PRO-ALA-TYR-SER-ARG-TYR-ILE-GLY-CYS, Urokinase-type plasminogen activator B
著者Wang, D, Yang, Y.S, Jiang, L.G, Huang, M.D, Li, J.Y, Andreasen, P.A, Xu, P, Chen, Z.
登録日2018-07-09
公開日2019-02-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.489 Å)
主引用文献Suppression of Tumor Growth and Metastases by Targeted Intervention in Urokinase Activity with Cyclic Peptides.
J.Med.Chem., 62, 2019
5AYR
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BU of 5ayr by Molmil
The crystal structure of SAUGI/human UDG complex
分子名称: MAGNESIUM ION, Uncharacterized protein, Uracil-DNA glycosylase
著者Wang, H.C, Ko, T.P, Huang, M.F, Wang, A.H.J.
登録日2015-09-02
公開日2016-06-08
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Using structural-based protein engineering to modulate the differential inhibition effects of SAUGI on human and HSV uracil DNA glycosylase.
Nucleic Acids Res., 44, 2016
4ZKO
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BU of 4zko by Molmil
The crystal structure of upain-1-W3A in complex with uPA at pH7.4
分子名称: C-terminal fragment of upain-1-W3A, HEXAETHYLENE GLYCOL, N-terminal fragment of upain-1-W3A, ...
著者Jiang, L, Andreasen, P.A, Huang, M.
登録日2015-04-30
公開日2016-05-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.29 Å)
主引用文献The crystal structure of mupain-1-IG in complex with murinised human uPA at pH7.4
To Be Published
4IRL
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BU of 4irl by Molmil
X-ray structure of the CARD domain of zebrafish GBP-NLRP1 like protein
分子名称: 1,2-ETHANEDIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ...
著者Jin, T, Huang, M, Smith, P, Xiao, T.
登録日2013-01-15
公開日2013-08-07
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Structure of the caspase-recruitment domain from a zebrafish guanylate-binding protein.
Acta Crystallogr.,Sect.F, 69, 2013
6AG3
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BU of 6ag3 by Molmil
Crystal structure of uPA in complex with 3,5-bis(azanyl)-N-carbamimidoyl-6-(2,4-dimethoxypyrimidin-5-yl)pyrazine-2-carboxamide
分子名称: 3,5-bis(azanyl)-N-carbamimidoyl-6-(2,4-dimethoxypyrimidin-5-yl)pyrazine-2-carboxamide, Urokinase-type plasminogen activator
著者Buckley, B, Jiang, L.G, Majed, H, Huang, M.D, Kelso, M, Ranson, M.
登録日2018-08-09
公開日2019-09-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献uPA-HMA
To Be Published
6AEX
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BU of 6aex by Molmil
Crystal structure of unoccupied murine uPAR
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Urokinase plasminogen activator surface receptor
著者Min, L, Huang, M.
登録日2018-08-06
公開日2019-07-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.393 Å)
主引用文献Crystal structure of the unoccupied murine urokinase-type plasminogen activator receptor (uPAR) reveals a tightly packed DII-DIII unit.
Febs Lett., 593, 2019
6AG9
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BU of 6ag9 by Molmil
Crystal structure of uPA in complex with 3,5-bis(azanyl)-6-(1-benzofuran-2-yl)-N-carbamimidoyl-pyrazine-2- carboxamide
分子名称: 3,5-bis(azanyl)-6-(1-benzofuran-2-yl)-N-carbamimidoyl-pyrazine-2-carboxamide, SULFATE ION, Urokinase-type plasminogen activator
著者Buckley, B, Jiang, L.G, Majed, H, Huang, M.D, Kelso, M, Ranson, M.
登録日2018-08-09
公開日2019-09-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献uPA-HMA
To Be Published
6AG2
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BU of 6ag2 by Molmil
uPA-HMA
分子名称: 3,5-bis(azanyl)-N-carbamimidoyl-6-(2-methoxypyrimidin-5-yl)pyrazine-2-carboxamide, SULFATE ION, Urokinase-type plasminogen activator
著者Buckley, B, Jiang, L.G, Huang, M.D, Kelso, M, Ranson, M.
登録日2018-08-09
公開日2019-09-18
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献uPA-HMA
To Be Published
8ITT
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BU of 8itt by Molmil
Crystal structure of lysophosphatidylcholine in complex with human serum albumin and myristate
分子名称: Albumin, MYRISTIC ACID, [1-MYRISTOYL-GLYCEROL-3-YL]PHOSPHONYLCHOLINE
著者Wang, Y, Jiang, L.G, Huang, M.D.
登録日2023-03-22
公開日2024-01-31
実験手法X-RAY DIFFRACTION (3.03 Å)
主引用文献Crystal structures of human serum albumin in complex with lysophosphatidylcholine.
Biophys.J., 122, 2023
3OY6
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BU of 3oy6 by Molmil
The crystal structure of uPA complex with peptide inhibitor MH036 at pH4.6
分子名称: MH036, Urokinase-type plasminogen activator
著者Jiang, L.G, Andreasen, P.A, Huang, M.D.
登録日2010-09-22
公開日2011-08-10
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献The binding mechanism of a peptidic cyclic serine protease inhibitor
J.Mol.Biol., 412, 2011
3OY5
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BU of 3oy5 by Molmil
The crystal structure of uPA complex with peptide inhibitor MH027 at pH7.4
分子名称: MH027, SULFATE ION, Urokinase-type plasminogen activator
著者Jiang, L.G, Andreasen, P.A, Huang, M.D.
登録日2010-09-22
公開日2011-08-10
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献The binding mechanism of a peptidic cyclic serine protease inhibitor
J.Mol.Biol., 412, 2011
3OX7
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BU of 3ox7 by Molmil
The crystal structure of uPA complex with peptide inhibitor MH027 at pH4.6
分子名称: MH027, SULFATE ION, TETRAETHYLENE GLYCOL, ...
著者Jiang, L.G, Andreasen, P.A, Huang, M.D.
登録日2010-09-21
公開日2011-08-10
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献The binding mechanism of a peptidic cyclic serine protease inhibitor
J.Mol.Biol., 412, 2011
4ZHL
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BU of 4zhl by Molmil
The crystal structure of mupain-1-IG in complex with murinised human uPA at pH7.4
分子名称: Urokinase-type plasminogen activator, mupain-1-IG
著者Jiang, L, Andreasen, P.A, Huang, M.
登録日2015-04-25
公開日2015-09-16
最終更新日2015-10-14
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Selection of High-Affinity Peptidic Serine Protease Inhibitors with Increased Binding Entropy from a Back-Flip Library of Peptide-Protease Fusions.
J.Mol.Biol., 427, 2015
3S87
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BU of 3s87 by Molmil
Structure of Yeast Ribonucleotide Reductase 1 with dGTP and ADP
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Ahmad, M.F, Kaushal, P.S, Wan, Q, Wijeratna, S.R, Huang, M, Dealwis, C.D.
登録日2011-05-27
公開日2012-04-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural and biochemical basis of lethal mutant R293A of yeast ribonucleotide reductase
To be Published
4ZHM
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BU of 4zhm by Molmil
The crystal structure of mupain-1--16-IG in complex with murinised human uPA at pH7.4
分子名称: Urokinase-type plasminogen activator, mupain-1-16-IG, piperidine-1-carboximidamide
著者Jiang, L, Andreasen, P.A, Huang, M.
登録日2015-04-25
公開日2015-09-16
最終更新日2015-10-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Selection of High-Affinity Peptidic Serine Protease Inhibitors with Increased Binding Entropy from a Back-Flip Library of Peptide-Protease Fusions.
J.Mol.Biol., 427, 2015

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件を2024-07-10に公開中

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