5AYS
Crystal structure of SAUGI/HSV UDG complex
Summary for 5AYS
| Entry DOI | 10.2210/pdb5ays/pdb |
| Related | 5AYR |
| Descriptor | Uracil-DNA glycosylase, Uncharacterized protein (3 entities in total) |
| Functional Keywords | dna mimic protein, dna mimicking, uracil-dna glycosylase inhibitor, uracil-dna glycosylase, herpes simplex virus, hydrolase inhibitor |
| Biological source | Human herpesvirus 1 (strain 17) (HHV-1) More |
| Total number of polymer chains | 4 |
| Total formula weight | 84578.52 |
| Authors | Wang, H.C.,Ko, T.P.,Huang, M.F.,Wang, A.H.J. (deposition date: 2015-09-02, release date: 2016-06-08, Last modification date: 2023-11-08) |
| Primary citation | Wang, H.C.,Ho, C.H.,Chou, C.C.,Ko, T.P.,Huang, M.F.,Hsu, K.C.,Wang, A.H. Using structural-based protein engineering to modulate the differential inhibition effects of SAUGI on human and HSV uracil DNA glycosylase. Nucleic Acids Res., 44:4440-4449, 2016 Cited by PubMed: 26980279DOI: 10.1093/nar/gkw185 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.09 Å) |
Structure validation
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