6AG7

The crystal structure of uPA in complex with HMA-55F

Summary for 6AG7

DescriptorUrokinase-type plasminogen activator, 3,5-diamino-N-carbamimidoyl-6-(1-methyl-1H-pyrazol-4-yl)pyrazine-2-carboxamide (3 entities in total)
Functional Keywordsurokinase, amiloride, hydrolase
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total molecular weight27861.69
Authors
Buckley, B.,Jiang, L.G.,Majed, H.,Huang, M.D.,Kelso, M.,Ranson, M. (deposition date: 2018-08-09, release date: 2019-08-14)
Primary citation
Buckley, B.,Jiang, L.G.,Huang, M.D.,Kelso, M.,Ranson, M.
uPA-HMA
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.9 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.22450 5.2% 3.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution