6AG7
The crystal structure of uPA in complex with HMA-55F
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (U) | Urokinase-type plasminogen activator | polymer | 245 | 27586.4 | 1 | UniProt (P00749) Pfam (PF00089) | Homo sapiens (Human) | uPA |
| 2 | B (U) | 3,5-diamino-N-carbamimidoyl-6-(1-methyl-1H-pyrazol-4-yl)pyrazine-2-carboxamide | non-polymer | 275.3 | 1 | Chemie (H55) | |||
| 3 | C (U) | water | water | 18.0 | 80 | Chemie (HOH) |
Sequence modifications
U: 16 - 242 (UniProt: P00749)
| PDB | External Database | Details |
|---|---|---|
| Ala 122 | Cys 299 | conflict |
| Gln 145 | Asn 322 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 27586.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 275.3 | |
| All* | Total formula weight | 27861.7 |
