1KQN
| Crystal structure of NMN/NaMN adenylyltransferase complexed with NAD | 分子名称: | NICOTINAMIDE MONONUCLEOTIDE ADENYLYL TRANSFERASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, XENON | 著者 | Zhou, T, Kurnasov, O, Tomchick, D.R, Binns, D.D, Grishin, N.V, Marquez, V.E, Osterman, A.L, Zhang, H. | 登録日 | 2002-01-07 | 公開日 | 2003-01-07 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of Human Nicotinamide/Nicotonic Acid Mononucleotide Adenylyltransferase. Basis for the dual substrate specificity and activation of the oncolytic agent tiazofurin. J.Biol.Chem., 277, 2003
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1KQO
| Crystal structure of NMN/NaMN adenylyltransferase complexed with deamido-NAD | 分子名称: | NICOTINAMIDE MONONUCLEOTIDE ADENYLYL TRANSFERASE, NICOTINIC ACID ADENINE DINUCLEOTIDE | 著者 | Zhou, T, Kurnasov, O, Tomchick, D.R, Binns, D.D, Grishin, N.V, Marquez, V.E, Osterman, A.L, Zhang, H. | 登録日 | 2002-01-07 | 公開日 | 2003-01-07 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure of Hhuman of Nicotinamide/Nicotinic Acid Mononucleotide Adenylyltransferase.
Basis for the dual substrate specificity and activation of the oncolytic agent tiazofurin. J.Biol.Chem., 277, 2002
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1KR2
| CRYSTAL STRUCTURE OF HUMAN NMN/NAMN ADENYLYL TRANSFERASE COMPLEXED WITH TIAZOFURIN ADENINE DINUCLEOTIDE (TAD) | 分子名称: | BETA-METHYLENE-THIAZOLE-4-CARBOXYAMIDE-ADENINE DINUCLEOTIDE, NICOTINAMIDE MONONUCLEOTIDE ADENYLYL TRANSFERASE | 著者 | Zhou, T, Kurnasov, O, Tomchick, D.R, Binns, D.D, Grishin, N.V, Marquez, V.E, Osterman, A.L, Zhang, H. | 登録日 | 2002-01-08 | 公開日 | 2003-01-08 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of Hhuman of Nicotinamide/Nicotinic Acid Mononucleotide Adenylyltransferase.
Basis for the dual substrate specificity and activation of the oncolytic agent tiazofurin. J.Biol.Chem., 277, 2002
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6J15
| Complex structure of GY-5 Fab and PD-1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, GY-5 heavy chain Fab, ... | 著者 | Chen, D, Tan, S, Zhang, H, Wang, H, Chai, Y, Qi, J, Yan, J, Gao, G.F. | 登録日 | 2018-12-27 | 公開日 | 2019-11-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | The FG Loop of PD-1 Serves as a "Hotspot" for Therapeutic Monoclonal Antibodies in Tumor Immune Checkpoint Therapy. Iscience, 14, 2019
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6A8R
| Crystal structure of DUX4 HD2 domain associated with ERG DNA binding site | 分子名称: | DNA (5'-D(P*AP*AP*TP*CP*TP*CP*AP*TP*CP*A)-3'), DNA (5'-D(P*TP*GP*AP*TP*GP*AP*GP*AP*TP*T)-3'), Double homeobox protein 4 | 著者 | Dong, X, Zhang, H, Cheng, N, Meng, G. | 登録日 | 2018-07-10 | 公開日 | 2018-10-24 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | DUX4HD2-DNAERGstructure reveals new insight into DUX4-Responsive-Element. Leukemia, 33, 2019
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7X7R
| Cryo-EM structure of a bacterial protein | 分子名称: | RAMP superfamily protein, RNA (36-MER), RNA (5'-R(P*AP*GP*UP*CP*CP*GP*GP*GP*GP*CP*AP*GP*AP*AP*AP*AP*UP*UP*GP*G)-3'), ... | 著者 | Yu, G, Wang, X, Deng, Z, Zhang, H. | 登録日 | 2022-03-10 | 公開日 | 2022-11-16 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structure and function of a bacterial type III-E CRISPR-Cas7-11 complex. Nat Microbiol, 7, 2022
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7X8A
| Cryo-EM structure of a bacterial protein complex | 分子名称: | CHAT domain protein, RAMP superfamily protein, RNA (33-MER), ... | 著者 | Yu, G, Wang, X, Deng, Z, Zhang, H. | 登録日 | 2022-03-11 | 公開日 | 2022-11-16 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structure and function of a bacterial type III-E CRISPR-Cas7-11 complex. Nat Microbiol, 7, 2022
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7XC7
| Cryo-EM structure of a bacterial protein complex | 分子名称: | CHAT domain protein, RAMP superfamily protein, RNA (33-MER), ... | 著者 | Yu, G, Wang, X, Deng, Z, Zhang, H. | 登録日 | 2022-03-23 | 公開日 | 2022-11-16 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structure and function of a bacterial type III-E CRISPR-Cas7-11 complex. Nat Microbiol, 7, 2022
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2L1F
| Structure of a conserved retroviral RNA packaging element by NMR spectroscopy and cryo-electron tomography | 分子名称: | RNA (65-MER), RNA (66-MER) | 著者 | Summers, M.F, Irobalieva, R.N, Tolbert, B, Smalls-Manty, A, Iyalla, K, Loeliger, K, D'Souza, V, Khant, H, Schmid, M, Garcia, E, Telesnitsky, A, Chiu, W, Miyazaki, Y. | 登録日 | 2010-07-28 | 公開日 | 2010-10-27 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of a conserved retroviral RNA packaging element by NMR spectroscopy and cryo-electron tomography. J.Mol.Biol., 404, 2010
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7X7A
| Cryo-EM structure of SbCas7-11 in complex with crRNA and target RNA | 分子名称: | RAMP superfamily protein, RNA (33-MER), ZINC ION | 著者 | Yu, G, Wang, X, Deng, Z, Zhang, H. | 登録日 | 2022-03-09 | 公開日 | 2022-11-16 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structure and function of a bacterial type III-E CRISPR-Cas7-11 complex. Nat Microbiol, 7, 2022
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3ZYP
| Cellulose induced protein, Cip1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CIP1, ... | 著者 | Jacobson, F, Karkehabadi, S, Hansson, H, Goedegebuur, F, Wallace, L, Mitchinson, C, Piens, K, Stals, I, Sandgren, M. | 登録日 | 2011-08-24 | 公開日 | 2012-09-12 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | The Crystal Structure of the Core Domain of a Cellulose Induced Protein (Cip1) from Hypocrea Jecorina, at 1.5 A Resolution. Plos One, 8, 2013
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5XEU
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4HZ9
| Crystal structure of the type VI native effector-immunity complex Tae3-Tai3 from Ralstonia pickettii | 分子名称: | Putative cytoplasmic protein, Putative periplasmic protein | 著者 | Dong, C, Zhang, H, Gao, Z.Q, Dong, Y.H. | 登録日 | 2012-11-14 | 公開日 | 2013-08-21 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural insights into the inhibition of type VI effector Tae3 by its immunity protein Tai3 Biochem.J., 454, 2013
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4M72
| Mutant structure of methyltransferase from Streptomyces hygroscopicus | 分子名称: | (2R)-2-hydroxy-3-phenylpropanoic acid, (2R,3R)-2-hydroxy-3-methoxy-3-phenylpropanoic acid, CALCIUM ION, ... | 著者 | Liu, Y.C, Zou, X.W, Chan, H.C, Huang, C.J, Li, T.L. | 登録日 | 2013-08-12 | 公開日 | 2014-06-25 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure and mechanism of a nonhaem-iron SAM-dependent C-methyltransferase and its engineering to a hydratase and an O-methyltransferase Acta Crystallogr.,Sect.D, 70, 2014
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4M6Y
| Mutant structure of methyltransferase from Streptomyces hygroscopicus complexed with S-adenosyl-L-homocysteine and methylphenylpyruvic acid | 分子名称: | (2R)-2-hydroxy-3-phenylpropanoic acid, (3R)-2-oxo-3-phenylbutanoic acid, CALCIUM ION, ... | 著者 | Liu, Y.C, Zou, X.W, Chan, H.C, Huang, C.J, Li, T.L. | 登録日 | 2013-08-12 | 公開日 | 2014-06-25 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure and mechanism of a nonhaem-iron SAM-dependent C-methyltransferase and its engineering to a hydratase and an O-methyltransferase Acta Crystallogr.,Sect.D, 70, 2014
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4M73
| Mutant structure of methyltransferase from Streptomyces hygroscopicus | 分子名称: | (2R)-2-hydroxy-3-phenylpropanoic acid, (2R,3R)-2-hydroxy-3-methoxy-3-phenylpropanoic acid, CALCIUM ION, ... | 著者 | Liu, Y.C, Zou, X.W, Chan, H.C, Huang, C.J, Li, T.L. | 登録日 | 2013-08-12 | 公開日 | 2014-06-25 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure and mechanism of a nonhaem-iron SAM-dependent C-methyltransferase and its engineering to a hydratase and an O-methyltransferase Acta Crystallogr.,Sect.D, 70, 2014
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4KYK
| Crystal structure of mouse glyoxalase I complexed with indomethacin | 分子名称: | INDOMETHACIN, Lactoylglutathione lyase, ZINC ION | 著者 | Zhai, J, Yuan, M, Zhang, L, Chen, Y, Zhang, H, Chen, S, Zhao, Y. | 登録日 | 2013-05-29 | 公開日 | 2013-08-07 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Zopolrestat as a human glyoxalase I inhibitor and its structural basis. Chemmedchem, 8, 2013
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3VUC
| Human renin in complex with compound 5 | 分子名称: | (2R,4S,5S)-5-amino-6-[4-(2-chlorophenyl)-2,2-dimethyl-5-oxopiperazin-1-yl]-2-ethyl-4-hydroxy-N-[(1R,2S,3S,5S,7S)-5-hydroxytricyclo[3.3.1.1~3,7~]dec-2-yl]hexanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Renin | 著者 | Takahashi, M, Matsui, Y, Hanzawa, H. | 登録日 | 2012-06-26 | 公開日 | 2013-05-15 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Discovery of DS-8108b, a Novel Orally Bioavailable Renin Inhibitor. Acs Med.Chem.Lett., 3, 2012
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6IMQ
| Crystal structure of PML B1-box multimers | 分子名称: | CHLORIDE ION, Protein PML, ZINC ION | 著者 | Li, Y, Ma, X, Chen, Z, Wu, H, Wang, P, Wu, W, Cheng, N, Zeng, L, Zhang, H, Cai, X, Chen, S.J, Chen, Z, Meng, G. | 登録日 | 2018-10-23 | 公開日 | 2019-07-31 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | B1 oligomerization regulates PML nuclear body biogenesis and leukemogenesis. Nat Commun, 10, 2019
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7E5N
| crystal structure of cis assembled TROP-2 | 分子名称: | Tumor-associated calcium signal transducer 2 | 著者 | Sun, M, Zhang, H, Chai, Y, Qi, J, Gao, G.F, Tan, S. | 登録日 | 2021-02-19 | 公開日 | 2021-12-15 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural insights into the cis and trans assembly of human trophoblast cell surface antigen 2. Iscience, 24, 2021
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7E5M
| crystal structure of trans assembled human TROP-2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Tumor-associated calcium signal transducer 2 | 著者 | Sun, M, Zhang, H, Chai, Y, Qi, J, Gao, G.F, Tan, S. | 登録日 | 2021-02-19 | 公開日 | 2021-12-15 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural insights into the cis and trans assembly of human trophoblast cell surface antigen 2. Iscience, 24, 2021
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3T8A
| Crystal structure of Mycobacterium tuberculosis MenB in complex with substrate analogue, OSB-NCoA | 分子名称: | 1,4-Dihydroxy-2-naphthoyl-CoA synthase, o-succinylbenzoyl-N-coenzyme A | 著者 | Li, H.-J, Li, X, Liu, N, Zhang, H, Truglio, J, Mishra, S, Kisker, C, Garcia-Diaz, M, Tonge, P. | 登録日 | 2011-08-01 | 公開日 | 2011-08-24 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.245 Å) | 主引用文献 | Mechanism of the Intramolecular Claisen Condensation Reaction Catalyzed by MenB, a Crotonase Superfamily Member. Biochemistry, 50, 2011
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6J0O
| Crystal structure of CERT START domain in complex with compound SC1 | 分子名称: | 2-[4-[2-fluoranyl-5-[3-(6-methylpyridin-2-yl)-1~{H}-pyrazol-4-yl]phenyl]phenyl]sulfonylethanol, LIPID-TRANSFER PROTEIN CERT, UNKNOWN ATOM OR ION | 著者 | Suzuki, M, Nakao, N, Ueno, M, Sakai, S, Egawa, D, Hanzawa, H, Kawasaki, S, Kumagai, K, Kobayashi, S, Hanada, K. | 登録日 | 2018-12-25 | 公開日 | 2019-02-27 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Natural ligand-nonmimetic inhibitors of the lipid-transfer protein CERT Commun Chem, 2019
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7W7H
| S Suis FakA-FakB2 complex structure | 分子名称: | OLEIC ACID, Predicted kinase related to dihydroxyacetone kinase, SULFATE ION, ... | 著者 | Shi, Y, Zang, N, Lou, N, Xu, Y, Sun, J, Huang, M, Zhang, H, Lu, H, Zhou, C, Feng, Y. | 登録日 | 2021-12-04 | 公開日 | 2022-09-21 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure and mechanism for streptococcal fatty acid kinase (Fak) system dedicated to host fatty acid scavenging. Sci Adv, 8, 2022
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7WIY
| Cryo-EM structure of human TPH2 tetramer | 分子名称: | FE (III) ION, IMIDAZOLE, Tryptophan 5-hydroxylase 2 | 著者 | Zhu, K.F, Liu, C, Zhang, H.W, Wang, D.P. | 登録日 | 2022-01-05 | 公開日 | 2022-10-05 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | 主引用文献 | Cryo-EM Structure and Activator Screening of Human Tryptophan Hydroxylase 2. Front Pharmacol, 13, 2022
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