1KQO

Crystal structure of NMN/NaMN adenylyltransferase complexed with deamido-NAD

Summary for 1KQO

Related1KQN
DescriptorNICOTINAMIDE MONONUCLEOTIDE ADENYLYL TRANSFERASE, NICOTINIC ACID ADENINE DINUCLEOTIDE (3 entities in total)
Functional Keywordsnucleotidyltransferase superfamily, transferase
Biological sourceHomo sapiens (human)
Cellular locationNucleus  Q9HAN9
Total number of polymer chains6
Total molecular weight195887.52
Authors
Zhou, T.,Kurnasov, O.,Tomchick, D.R.,Binns, D.D.,Grishin, N.V.,Marquez, V.E.,Osterman, A.L.,Zhang, H. (deposition date: 2002-01-07, release date: 2003-01-07, Last modification date: 2014-10-22)
Primary citation
Zhou, T.,Kurnasov, O.,Tomchick, D.R.,Binns, D.D.,Grishin, N.V.,Marquez, V.E.,Osterman, A.L.,Zhang, H.
Structure of Hhuman of Nicotinamide/Nicotinic Acid Mononucleotide Adenylyltransferase. Basis for the dual substrate specificity and activation of the oncolytic agent tiazofurin.
J.Biol.Chem., 277:13148-13154, 2002
PubMed: 11788603 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M111469200
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.5 Å)
?

Structure validation

ClashscoreRamachandran outliersSidechain outliers150.5%4.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload