6IMQ

Crystal structure of PML B1-box multimers

Summary for 6IMQ

• Entry DOI: 10.2210/pdb6imq/pdb
• Descriptor: Protein PML, ZINC ION, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: trim19, pml, nuclear body, b1-box, pml-rara, apl, leukemia, oncoprotein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 4
• Total formula weight: 24325.91

Authors

Li, Y.,Ma, X.,Chen, Z.,Wu, H.,Wang, P.,Wu, W.,Cheng, N.,Zeng, L.,Zhang, H.,Cai, X.,Chen, S.J.,Chen, Z.,Meng, G. (deposition date: 2018-10-23, release date: 2019-07-31, Last modification date: 2024-03-27)

• Primary citation: Li, Y.,Ma, X.,Chen, Z.,Wu, H.,Wang, P.,Wu, W.,Cheng, N.,Zeng, L.,Zhang, H.,Cai, X.,Chen, S.J.,Chen, Z.,Meng, G.; B1 oligomerization regulates PML nuclear body biogenesis and leukemogenesis.; Nat Commun, 10:3789-3789, 2019; PubMed: 31439836; DOI: 10.1038/s41467-019-11746-0

Experimental method

X-RAY DIFFRACTION (2.06 Å)