7WIY

Cryo-EM structure of human TPH2 tetramer

Summary for 7WIY

Entry DOI	10.2210/pdb7wiy/pdb
EMDB information	32540
Descriptor	Tryptophan 5-hydroxylase 2, FE (III) ION, IMIDAZOLE (3 entities in total)
Functional Keywords	human, tryptophan 5-hydroxylase 2, tetramer, biosynthetic protein
Biological source	Homo sapiens (human)
Total number of polymer chains	4
Total formula weight	225018.16
Authors	Zhu, K.F.,Liu, C.,Zhang, H.W.,Wang, D.P. (deposition date: 2022-01-05, release date: 2022-10-05, Last modification date: 2024-06-26)
Primary citation	Zhu, K.,Liu, C.,Gao, Y.,Lu, J.,Wang, D.,Zhang, H. Cryo-EM Structure and Activator Screening of Human Tryptophan Hydroxylase 2. Front Pharmacol, 13:907437-907437, 2022 Cited by PubMed: 36046836 DOI: 10.3389/fphar.2022.907437 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.09 Å)

Structure validation