3T8A
Crystal structure of Mycobacterium tuberculosis MenB in complex with substrate analogue, OSB-NCoA
Summary for 3T8A
Entry DOI | 10.2210/pdb3t8a/pdb |
Related | 3T88 3T89 3T8B |
Descriptor | 1,4-Dihydroxy-2-naphthoyl-CoA synthase, o-succinylbenzoyl-N-coenzyme A (3 entities in total) |
Functional Keywords | crotonase superfamily, lyase-lyase inhibitor complex, lyase/lyase inhibitor |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 3 |
Total formula weight | 112619.23 |
Authors | Li, H.-J.,Li, X.,Liu, N.,Zhang, H.,Truglio, J.,Mishra, S.,Kisker, C.,Garcia-Diaz, M.,Tonge, P. (deposition date: 2011-08-01, release date: 2011-08-24, Last modification date: 2023-09-13) |
Primary citation | Li, H.J.,Li, X.,Liu, N.,Zhang, H.,Truglio, J.J.,Mishra, S.,Kisker, C.,Garcia-Diaz, M.,Tonge, P.J. Mechanism of the Intramolecular Claisen Condensation Reaction Catalyzed by MenB, a Crotonase Superfamily Member. Biochemistry, 50:9532-9544, 2011 Cited by PubMed: 21830810DOI: 10.1021/bi200877x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.245 Å) |
Structure validation
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