6J15
Complex structure of GY-5 Fab and PD-1
Summary for 6J15
Entry DOI | 10.2210/pdb6j15/pdb |
Descriptor | Programmed cell death protein 1, GY-5 heavy chain Fab, GY-5 light chain Fab, ... (6 entities in total) |
Functional Keywords | tumor immunotherapy, complex structure, fg loop, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 124296.08 |
Authors | |
Primary citation | Chen, D.,Tan, S.,Zhang, H.,Wang, H.,He, W.,Shi, R.,Tong, Z.,Zhu, J.,Cheng, H.,Gao, S.,Chai, Y.,Qi, J.,Xiao, M.,Yan, J.,Gao, G.F. The FG Loop of PD-1 Serves as a "Hotspot" for Therapeutic Monoclonal Antibodies in Tumor Immune Checkpoint Therapy. Iscience, 14:113-124, 2019 Cited by PubMed: 30952089DOI: 10.1016/j.isci.2019.03.017 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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