7E5M

crystal structure of trans assembled human TROP-2

Summary for 7E5M

• Entry DOI: 10.2210/pdb7e5m/pdb
• Descriptor: Tumor-associated calcium signal transducer 2, 2-acetamido-2-deoxy-beta-D-glucopyranose (2 entities in total)
• Functional Keywords: trop-2, crystal, sacituzumab, assembly, tumor, cell adhesion
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 53600.95

Authors

Sun, M.,Zhang, H.,Chai, Y.,Qi, J.,Gao, G.F.,Tan, S. (deposition date: 2021-02-19, release date: 2021-12-15, Last modification date: 2023-11-29)

• Primary citation: Sun, M.,Zhang, H.,Jiang, M.,Chai, Y.,Qi, J.,Gao, G.F.,Tan, S.; Structural insights into the cis and trans assembly of human trophoblast cell surface antigen 2.; Iscience, 24:103190-103190, 2021; PubMed: 34693228; DOI: 10.1016/j.isci.2021.103190

Experimental method

X-RAY DIFFRACTION (3.2 Å)