5MUB
 
 | | ACC1 Fab fragment in complex with citrullinated C1 epitope of CII (CG05) | | 分子名称: | ACC1 Fab fragment heavy chain, ACC1 Fab fragment light chain, triple-helical peptide containing the citrullinated C1 epitope of collagen type II,Collagen alpha-1(II) chain,triple-helical peptide containing the citrullinated C1 epitope of collagen type II | | 著者 | Dobritzsch, D, Holmdahl, R, Ge, C. | | 登録日 | 2017-01-13 | | 公開日 | 2017-07-19 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Anti-citrullinated protein antibodies cause arthritis by cross-reactivity to joint cartilage.
JCI Insight, 2, 2017
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5MU2
 | | ACC1 Fab fragment in complex with CII583-591 (CG10) | | 分子名称: | ACC1 Fab fragment heavy chain, ACC1 Fab fragment light chain, synthetic peptide containing the CII583-591 epitope of collagen type II | | 著者 | Dobritzsch, D, Holmdahl, R, Ge, C. | | 登録日 | 2017-01-12 | | 公開日 | 2017-07-19 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Anti-citrullinated protein antibodies cause arthritis by cross-reactivity to joint cartilage.
JCI Insight, 2, 2017
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5MU0
 | | ACC1 Fab fragment in complex with citrullinated C1 epitope of CII (IA03) | | 分子名称: | IA03 peptide containing the citrullinated C1 epitope of collagen type II,Collagen alpha-1(II) chain,IA03 peptide containing the citrullinated C1 epitope of collagen type II, heavy chain of ACC1 antibody Fab fragment, light chain of ACC1 antibody Fab fragment | | 著者 | Dobritzsch, D, Holmdahl, R, Ge, C. | | 登録日 | 2017-01-11 | | 公開日 | 2017-07-19 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Anti-citrullinated protein antibodies cause arthritis by cross-reactivity to joint cartilage.
JCI Insight, 2, 2017
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5MV3
 | | ACC1 Fab fragment in complex with CII583-591 (CG10) | | 分子名称: | heavy chain of ACC1 Fab fragment, light chain of ACC1 Fab fragment, synthetic peptide containing the CII583-591 epitope of collagen type II,Collagen alpha-1(II) chain,synthetic peptide containing the CII583-591 epitope of collagen type II, | | 著者 | Dobritzsch, D, Holmdahl, R, Ge, C. | | 登録日 | 2017-01-15 | | 公開日 | 2017-07-19 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Anti-citrullinated protein antibodies cause arthritis by cross-reactivity to joint cartilage.
JCI Insight, 2, 2017
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5MV4
 | | ACC1 Fab fragment in complex with citrullinated CII616-639 epitope of collagen type II (ptm23) | | 分子名称: | ACC1 antibody Fab fragment, heavy chain, light chain, ... | | 著者 | Dobritzsch, D, Holmdahl, R, Ge, C. | | 登録日 | 2017-01-15 | | 公開日 | 2017-07-19 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Anti-citrullinated protein antibodies cause arthritis by cross-reactivity to joint cartilage.
JCI Insight, 2, 2017
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5OD8
 | | Crystal structure of the RA-associated mAb B2 (Fab fragment) | | 分子名称: | B2 Fab fragment - Light chain, B2 Fab fragment - heavy chain | | 著者 | Dobritzsch, D, Ge, C, Holmdahl, R, Amara, K, Malmstrom, V. | | 登録日 | 2017-07-05 | | 公開日 | 2018-07-04 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural Basis of Cross-Reactivity of Anti-Citrullinated Protein Antibodies.
Arthritis Rheumatol, 71, 2019
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5OD0
 | | Crystal structure of ACPA E4 | | 分子名称: | Fab fragment of ACPA E4 - Light chain, Fab fragment of ACPA E4 - heavy chain, GLYCEROL | | 著者 | Dobritzsch, D, Ge, C, Holmdahl, R. | | 登録日 | 2017-07-04 | | 公開日 | 2018-07-04 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural Basis of Cross-Reactivity of Anti-Citrullinated Protein Antibodies.
Arthritis Rheumatol, 71, 2019
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5OCY
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5OCK
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5ODB
 | | Crystal structure of the RA-associated mAb D10 (chimeric Fab fragment) | | 分子名称: | D10 Fab fragment - heavy chain, D10 Fab fragment - light chain, GLYCEROL, ... | | 著者 | Dobritzsch, D, Ge, C, Holmdahl, R, Amara, K, Malmstrom, V. | | 登録日 | 2017-07-05 | | 公開日 | 2018-07-04 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | Structural Basis of Cross-Reactivity of Anti-Citrullinated Protein Antibodies.
Arthritis Rheumatol, 71, 2019
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5OCX
 | | Crystal structure of ACPA E4 in complex with CII-C-13-CIT | | 分子名称: | 1,2-ETHANEDIOL, CII-C-13-CIT, Fab fragment anti-citrullinated protein antibody E4 - light chain, ... | | 著者 | Dobritzsch, D, Ge, C, Holmdahl, R. | | 登録日 | 2017-07-04 | | 公開日 | 2018-07-04 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structural Basis of Cross-Reactivity of Anti-Citrullinated Protein Antibodies.
Arthritis Rheumatol, 71, 2019
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8BBR
 | | Determination of the structure of active tyrosinase from bacterium Verrucomicrobium spinosum | | 分子名称: | COPPER (II) ION, Core tyrosinase, SULFATE ION | | 著者 | Fekry, M, Dave, K, Badgujar, D, Aurelius, O, Hamnevik, E, Dobritzsch, D, Danielson, H. | | 登録日 | 2022-10-14 | | 公開日 | 2023-09-20 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | The Crystal Structure of Tyrosinase from Verrucomicrobium spinosum Reveals It to Be an Atypical Bacterial Tyrosinase.
Biomolecules, 13, 2023
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2R6S
 | | Crystal structure of Gab protein | | 分子名称: | BICINE, FE (II) ION, GLYCEROL, ... | | 著者 | Lohkamp, B, Dobritzsch, D. | | 登録日 | 2007-09-06 | | 公開日 | 2008-06-03 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | A mixture of fortunes: the curious determination of the structure of Escherichia coli BL21 Gab protein.
Acta Crystallogr.,Sect.D, 64, 2008
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6YUH
 | | Crystal structure of SMYD3 with diperodon R enantiomer bound to allosteric site | | 分子名称: | Diperodon, GLYCEROL, Histone-lysine N-methyltransferase SMYD3, ... | | 著者 | Cederfelt, D, Talibov, V.O, Dobritzsch, D, Danielson, U.H. | | 登録日 | 2020-04-27 | | 公開日 | 2021-01-13 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Discovery of an Allosteric Ligand Binding Site in SMYD3 Lysine Methyltransferase.
Chembiochem, 22, 2021
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8BBQ
 | | Determination of the structure of active tyrosinase from bacterium Verrucomicrobium spinosum | | 分子名称: | COPPER (II) ION, Core tyrosinase, GLYCEROL, ... | | 著者 | Fekry, M, Dave, K, Badgujar, D, Aurelius, O, Hamnevik, E, Dobritzsch, D, Danielson, H. | | 登録日 | 2022-10-14 | | 公開日 | 2023-09-20 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | | 主引用文献 | The Crystal Structure of Tyrosinase from Verrucomicrobium spinosum Reveals It to Be an Atypical Bacterial Tyrosinase.
Biomolecules, 13, 2023
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7BJ1
 | | Crystal structure of SMYD3 with diperodon S enantiomer bound to allosteric site | | 分子名称: | ACETATE ION, Diperodon (S-enantiomer), GLYCEROL, ... | | 著者 | Talibov, V.O, Cederfelt, D, Dobritzsch, D, Danielson, U.H. | | 登録日 | 2021-01-13 | | 公開日 | 2021-03-03 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | | 主引用文献 | Discovery of an Allosteric Ligand Binding Site in SMYD3 Lysine Methyltransferase
Chembiochem, 22, 2021
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1QPB
 | | PYRUVATE DECARBOYXLASE FROM YEAST (FORM B) COMPLEXED WITH PYRUVAMIDE | | 分子名称: | MAGNESIUM ION, PYRUVAMIDE, PYRUVATE DECARBOXYLASE (FORM B), ... | | 著者 | Lu, G, Dobritzsch, D, Schneider, G. | | 登録日 | 1999-11-26 | | 公開日 | 2000-02-04 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | The Structural Basis of Substrate Activation in Yeast Pyruvate Decarboxylase a Crystallographic and Kinetic Study
Eur.J.Biochem., 267, 2000
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2FTW
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8PT4
 | | beta-Ureidopropionase tetramer | | 分子名称: | Beta-ureidopropionase | | 著者 | Cederfelt, D, Dobritzsch, D. | | 登録日 | 2023-07-13 | | 公開日 | 2024-01-10 | | 実験手法 | ELECTRON MICROSCOPY (3.33 Å) | | 主引用文献 | The Allosteric Regulation of Beta-Ureidopropionase Depends on Fine-Tuned Stability of Active-Site Loops and Subunit Interfaces.
Biomolecules, 13, 2023
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7NZF
 | | Crystal structure of HLA-DR4 in complex with a mutated human collagen type II peptide | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DR alpha chain, ... | | 著者 | Ge, C, Dobritzsch, D, Holmdahl, R. | | 登録日 | 2021-03-24 | | 公開日 | 2022-05-11 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Key interactions in the trimolecular complex consisting of the rheumatoid arthritis-associated DRB1*04:01 molecule, the major glycosylated collagen II peptide and the T-cell receptor.
Ann Rheum Dis, 81, 2022
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7NZE
 | | Crystal structure of HLA-DR4 in complex with a human collagen type II peptide | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Collagen alpha-1(II) chain, GLYCEROL, ... | | 著者 | Ge, C, Dobritzsch, D, Holmdahl, R. | | 登録日 | 2021-03-24 | | 公開日 | 2022-06-08 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Key interactions in the trimolecular complex consisting of the rheumatoid arthritis-associated DRB1*04:01 molecule, the major glycosylated collagen II peptide and the T-cell receptor.
Ann Rheum Dis, 81, 2022
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7NDP
 | | X-ray structure of acetylcholine-binding protein (AChBP) in complex with FL001856. | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 6-bromanylspiro[3~{H}-chromene-2,4'-piperidine]-4-one, ... | | 著者 | Cederfelt, D, Boronat, P, Dobritzsch, D, Hennig, S, Fitzgerald, E.A, de Esch, I.J.P, Danielson, U.H. | | 登録日 | 2021-02-02 | | 公開日 | 2021-04-07 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Discovery of fragments inducing conformational effects in dynamic proteins using a second-harmonic generation biosensor.
Rsc Adv, 11, 2021
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7ZX4
 | | Clathrin N-terminal domain in complex with a HURP phospho-peptide | | 分子名称: | CHLORIDE ION, Clathrin heavy chain 1, Disks large-associated protein 5, ... | | 著者 | Kliche, J, Badgujar, D, Dobritzsch, D, Ivarsson, Y. | | 登録日 | 2022-05-20 | | 公開日 | 2023-03-29 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | | 主引用文献 | Large-scale phosphomimetic screening identifies phospho-modulated motif-based protein interactions.
Mol.Syst.Biol., 19, 2023
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7NDV
 | | X-ray structure of acetylcholine-binding protein (AChBP) in complex with FL001888. | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[4-(trifluoromethyl)phenoxy]piperidine, Acetylcholine-binding protein, ... | | 著者 | Cederfelt, D, Boronat, P, Dobritzsch, D, Hennig, S, Fitzgerald, E.A, de Esch, I.J.P, Danielson, U.H. | | 登録日 | 2021-02-02 | | 公開日 | 2021-04-07 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Discovery of fragments inducing conformational effects in dynamic proteins using a second-harmonic generation biosensor
RSC Advances, 11, 2021
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1ZPD
 | | PYRUVATE DECARBOXYLASE FROM ZYMOMONAS MOBILIS | | 分子名称: | CITRIC ACID, MAGNESIUM ION, MONO-{4-[(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-AMINO]-2-HYDROXY-3-MERCAPTO-PENT-3-ENYL-PHOSPHONO} ESTER, ... | | 著者 | Lu, G, Dobritzsch, D, Schneider, G. | | 登録日 | 1998-04-17 | | 公開日 | 1999-02-02 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | High resolution crystal structure of pyruvate decarboxylase from Zymomonas mobilis. Implications for substrate activation in pyruvate decarboxylases.
J.Biol.Chem., 273, 1998
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