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5ODB

Crystal structure of the RA-associated mAb D10 (chimeric Fab fragment)

Summary for 5ODB
Entry DOI10.2210/pdb5odb/pdb
DescriptorD10 Fab fragment - heavy chain, D10 Fab fragment - light chain, SULFATE ION, ... (5 entities in total)
Functional Keywordsantibody fab fragment, immune system rheumatoid arthritis associated, immune system
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains2
Total formula weight47021.15
Authors
Dobritzsch, D.,Ge, C.,Holmdahl, R.,Amara, K.,Malmstrom, V. (deposition date: 2017-07-05, release date: 2018-07-04, Last modification date: 2024-01-17)
Primary citationGe, C.,Xu, B.,Liang, B.,Lonnblom, E.,Lundstrom, S.L.,Zubarev, R.A.,Ayoglu, B.,Nilsson, P.,Skogh, T.,Kastbom, A.,Malmstrom, V.,Klareskog, L.,Toes, R.E.M.,Rispens, T.,Dobritzsch, D.,Holmdahl, R.
Structural Basis of Cross-Reactivity of Anti-Citrullinated Protein Antibodies.
Arthritis Rheumatol, 71:210-221, 2019
Cited by
PubMed: 30152126
DOI: 10.1002/art.40698
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.53 Å)
Structure validation

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