5OCK
Crystal structure of ACPA E4 in complex with CEP1
Summary for 5OCK
Entry DOI | 10.2210/pdb5ock/pdb |
Descriptor | Human ACPA E4 Fab fragment - Light chain, Human ACPA E4 Fab fragment - Heavy chain, CEP1 peptide (from enolase), ... (4 entities in total) |
Functional Keywords | anti-citrullinated protein antibody fab fragment, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 49482.07 |
Authors | Dobritzsch, D.,Ge, C.,Holmdahl, R. (deposition date: 2017-07-03, release date: 2018-07-04, Last modification date: 2024-01-17) |
Primary citation | Ge, C.,Xu, B.,Liang, B.,Lonnblom, E.,Lundstrom, S.L.,Zubarev, R.A.,Ayoglu, B.,Nilsson, P.,Skogh, T.,Kastbom, A.,Malmstrom, V.,Klareskog, L.,Toes, R.E.M.,Rispens, T.,Dobritzsch, D.,Holmdahl, R. Structural Basis of Cross-Reactivity of Anti-Citrullinated Protein Antibodies. Arthritis Rheumatol, 71:210-221, 2019 Cited by PubMed: 30152126DOI: 10.1002/art.40698 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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