7NDV

X-ray structure of acetylcholine-binding protein (AChBP) in complex with FL001888.

Summary for 7NDV

• Entry DOI: 10.2210/pdb7ndv/pdb
• Descriptor: Acetylcholine-binding protein, 4-[4-(trifluoromethyl)phenoxy]piperidine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: fragment based drug design, acetylcholine-binding protein, choline-binding protein
• Biological source: Lymnaea stagnalis (Great pond snail, Helix stagnalis)
• Total number of polymer chains: 10
• Total formula weight: 274300.66

Authors

Cederfelt, D.,Boronat, P.,Dobritzsch, D.,Hennig, S.,Fitzgerald, E.A.,de Esch, I.J.P.,Danielson, U.H. (deposition date: 2021-02-02, release date: 2021-04-07, Last modification date: 2024-01-31)

• Primary citation: Fitzgerald, E.A.,Butko, M.T.,Boronat, P.,Cederfelt, D.,Abramsson, M.,Ludviksdottir, H.,van Muijlwijk-Koezen, J.,de Esch, I.J.P.,Dobritzsch, D.,Young, T.,Danielson, U.H.; Discovery of fragments inducing conformational effects in dynamic proteins using a second-harmonic generation biosensor; RSC Advances, 11:7527-7537, 2021

Experimental method

X-RAY DIFFRACTION (1.7 Å)