7NDP

X-ray structure of acetylcholine-binding protein (AChBP) in complex with FL001856.

Summary for 7NDP

• Entry DOI: 10.2210/pdb7ndp/pdb
• Descriptor: Acetylcholine-binding protein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• Functional Keywords: fragment based drug design, acetylcholine-binding protein, choline-binding protein
• Biological source: Lymnaea stagnalis (Great pond snail)
• Total number of polymer chains: 10
• Total formula weight: 275351.57

Authors

Cederfelt, D.,Boronat, P.,Dobritzsch, D.,Hennig, S.,Fitzgerald, E.A.,de Esch, I.J.P.,Danielson, U.H. (deposition date: 2021-02-02, release date: 2021-04-07, Last modification date: 2024-01-31)

• Primary citation: FitzGerald, E.A.,Butko, M.T.,Boronat, P.,Cederfelt, D.,Abramsson, M.,Ludviksdottir, H.,van Muijlwijk-Koezen, J.E.,de Esch, I.J.P.,Dobritzsch, D.,Young, T.,Danielson, U.H.; Discovery of fragments inducing conformational effects in dynamic proteins using a second-harmonic generation biosensor.; Rsc Adv, 11:7527-7537, 2021; PubMed: 35423271; DOI: 10.1039/d0ra09844b

Experimental method

X-RAY DIFFRACTION (2 Å)