5MU2

ACC1 Fab fragment in complex with CII583-591 (CG10)

Summary for 5MU2

Entry DOI	10.2210/pdb5mu2/pdb
Descriptor	ACC1 Fab fragment heavy chain, ACC1 Fab fragment light chain, synthetic peptide containing the CII583-591 epitope of collagen type II, ... (4 entities in total)
Functional Keywords	anti-citrullinated protein antibody (acpa) fab fragment collagen type ii, immune system
Biological source	Mus musculus (House mouse) More
Total number of polymer chains	24
Total formula weight	398186.26
Authors	Dobritzsch, D.,Holmdahl, R.,Ge, C. (deposition date: 2017-01-12, release date: 2017-07-19, Last modification date: 2024-01-17)
Primary citation	Ge, C.,Tong, D.,Liang, B.,Lonnblom, E.,Schneider, N.,Hagert, C.,Viljanen, J.,Ayoglu, B.,Stawikowska, R.,Nilsson, P.,Fields, G.B.,Skogh, T.,Kastbom, A.,Kihlberg, J.,Burkhardt, H.,Dobritzsch, D.,Holmdahl, R. Anti-citrullinated protein antibodies cause arthritis by cross-reactivity to joint cartilage. JCI Insight, 2:-, 2017 Cited by PubMed: 28679953 DOI: 10.1172/jci.insight.93688 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation